Skip to main navigation
Skip to main content
Skip to footer
For
Medicare
For
Providers
For
Brokers
For
Employers
Español
For Individuals & Families:
For Individuals & Families
Medical
Dental
Other Supplemental
Explore coverage through work
How to Buy Health Insurance
Types of Dental Insurance
Open Enrollment vs. Special Enrollment
See all topics
Shop for Medicare plans
Member Guide
Find a Doctor
Log in to myCigna
Home
Knowledge Center
Wellness Library
donepezil (oral)
donepezil (oral)
What is the most important information I should know about donepezil?
What is the most important information I should know about donepezil?
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
What is donepezil?
What is donepezil?
Donepezil is used to help improve mental function in people with Alzheimer's disease.
Donepezil does not work the same in all people. Some people taking this medicine have improved mental function, while others may have unchanged or even worsening mental function.
Donepezil is not a cure for Alzheimer's disease. This condition will progress over time, even in people who take donepezil.
Donepezil may also be used for other purposes not listed in this medication guide.
What should I discuss with my healthcare provider before taking donepezil?
What should I discuss with my healthcare provider before taking donepezil?
You should not use this medicine if you are allergic to donepezil or certain other drugs. Tell your doctor if you are allergic to any medicines.
Tell your doctor if you have ever had:
- a heart rhythm disorder;
- a stomach ulcer;
- urination problems;
- asthma or other breathing disorder;
- liver or kidney disease;
- a seizure; or
- trouble swallowing tablets.
Tell your doctor if you are pregnant or breast-feeding.
How should I take donepezil?
How should I take donepezil?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
You may take donepezil with or without food.
Swallow the regular tablet whole and do not crush, chew, or break it.
Remove an orally disintegrating tablet from the package only when you are ready to take the medicine. Place the tablet in your mouth and allow it to dissolve, without chewing. Swallow several times as the tablet dissolves. After the tablet dissolves completely, drink a glass of water.
If you need surgery or dental work, tell the surgeon or dentist ahead of time that you are using donepezil. You may need to stop using the medicine for a short time.
You should not stop using donepezil without your doctor's advice.
Store at room temperature away from moisture and heat.
What happens if I miss a dose?
What happens if I miss a dose?
Skip the missed dose and use your next dose at the regular time. Do not use two doses at one time.
If you miss your doses for more than 7 days in a row, call your doctor before taking the medicine again.
What happens if I overdose?
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include severe nausea, vomiting, drooling, sweating, blurred vision, feeling light-headed, slow heartbeat, shallow breathing, muscle weakness, fainting, or seizure (convulsions).
What should I avoid while taking donepezil?
What should I avoid while taking donepezil?
Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.
What are the possible side effects of donepezil?
What are the possible side effects of donepezil?
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
- slow heartbeats;
- a light-headed feeling, like you might pass out;
- new or worsening stomach pain, heartburn, nausea, or vomiting;
- a seizure;
- painful or difficult urination;
- new or worsening breathing problems; or
- signs of stomach bleeding --bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds.
Common side effects may include:
- nausea, vomiting, diarrhea;
- loss of appetite;
- muscle pain;
- sleep problems (insomnia); or
- feeling tired.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect donepezil?
What other drugs will affect donepezil?
Ask your doctor before taking a nonsteroidal anti-inflammatory drug (NSAID) such as aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib (Celebrex), diclofenac, indomethacin, meloxicam, and others. Using an NSAID with donepezil may increase your risk of stomach ulcer.
Other drugs may affect donepezil, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.
Where can I get more information?
Where can I get more information?
Your pharmacist can provide more information about donepezil.
This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.
Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.
<cipublic-spinner variant="large"><span>Loading…</span></cipublic-spinner>