Skip to main navigation Skip to main content Skip to footer For Medicare For Providers For Brokers For Employers Español For Individuals & Families: For Individuals & Families Medical Dental Other Supplemental Explore coverage through work How to Buy Health Insurance Types of Dental Insurance Open Enrollment vs. Special Enrollment See all topics Shop for Medicare plans Member Guide Find a Doctor Log in to myCigna
Home Knowledge Center Wellness Library eravacycline

eravacycline

Pronunciation: ER a va SYE kleen

Brand: Xerava

What is the most important information I should know about eravacycline?

What is the most important information I should know about eravacycline?

You should not use this medicine if you are allergic to any tetracycline antibiotic.

Using eravacycline during pregnancy may affect tooth and bone development in the unborn baby.

Eravacycline is not approved for use by anyone younger than 18 years old. Eravacycline can cause permanent yellowing or graying of the teeth in children.

What is eravacycline?

What is eravacycline?

Eravacycline is a tetracycline antibiotic that is used to treat serious stomach infections in adults.

Eravacycline may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before using eravacycline?

What should I discuss with my healthcare provider before using eravacycline?

You should not use this medicine if you are allergic to eravacycline or other tetracycline antibiotics such as demeclocycline, doxycycline, minocycline, tetracycline, or tigecycline.

Tell your doctor if you have ever had:

  • liver disease.

Using eravacycline during the second or third trimester of pregnancy may affect tooth and bone development in the unborn baby. This could cause permanent tooth discoloration later in the baby's life.

Eravacycline can pass into breast milk and may affect bone and tooth development in a nursing infant. Do not breastfeed while you are using eravacycline, and for at least 4 days after your last dose.

Eravacycline is not approved for use by anyone younger than 18 years old. Eravacycline can cause permanent yellowing or graying of the teeth in children.

How should I use eravacycline?

How should I use eravacycline?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Eravacycline is given as an infusion into a vein. A healthcare provider will give your first dose and may teach you how to properly use the medication by yourself.

Read and carefully follow any Instructions for Use provided with your medicine. Do not use eravacycline if you don't understand all instructions for proper use. Ask your doctor or pharmacist if you have questions.

Eravacycline must be given slowly, and the infusion can take at least 1 hour to complete.

Prepare your injection only when you are ready to give it. Do not use if the medicine looks cloudy, has changed colors, or has particles in it. Call your pharmacist for new medicine.

Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of infection that is resistant to medication. Eravacycline will not treat a viral infection such as the flu or a common cold.

Store unmixed eravacycline powder in the refrigerator, do not freeze.

Mixed eravacycline must be used within 6 hours if you keep it at room temperature, or 24 hours if kept in a refrigerator. Do not freeze.

Each single-use vial (bottle) of this medicine is for one use only. Throw it away after one use, even if there is still medicine left inside.

What happens if I miss a dose?

What happens if I miss a dose?

Use the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not use two doses at one time.

What happens if I overdose?

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using eravacycline?

What should I avoid while using eravacycline?

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor before using anti-diarrhea medicine.

Eravacycline could make you sunburn more easily. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

What are the possible side effects of eravacycline?

What are the possible side effects of eravacycline?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • severe stomach pain, diarrhea that is watery or bloody (may occur up to 2 months after your last dose of eravacycline);
  • severe headaches, dizziness, ringing in your ears, vision problems;
  • severe pain in your upper stomach spreading to your back, nausea and vomiting; or
  • signs of a fungal infection --skin itching or crusting, white patches in your mouth, vaginal itching or discharge, problems with your fingernails or toenails.

Common side effects may include:

  • nausea, vomiting; or
  • pain, bruising, redness, swelling, burning, or irritation around the IV needle.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect eravacycline?

What other drugs will affect eravacycline?

Tell your doctor about all your other medicines, especially:

  • enzalutamide;
  • mitotane;
  • rifampin;
  • St. John's wort; or
  • a blood thinner --warfarin, Coumadin, Jantoven; or
  • seizure medicine --carbamazepine, phenytoin.

This list is not complete. Other drugs may affect eravacycline, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Where can I get more information?

Where can I get more information?

Your pharmacist can provide more information about eravacycline.

This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.

Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.

<cipublic-spinner variant="large"><span>Loading…</span></cipublic-spinner>

Page Footer

I want to...

Get an ID card File a claim View my claims and EOBs Check coverage under my plan See prescription drug list Find an in-network doctor, dentist, or facility Find a form Find 1095-B tax form information View the Cigna Glossary Contact Cigna

Audiences

Individuals and Families Medicare Employers Brokers Providers

Secure Member Sites

myCigna member portal Health Care Provider portal Cigna for Employers Client Resource Portal Cigna for Brokers

Cigna Company Information

About Cigna Company Profile Careers Newsroom Investors Suppliers Third Party Administrators International Evernorth

 Cigna. All rights reserved.

Privacy Legal Product Disclosures Cigna Company Names Customer Rights Accessibility Non-Discrimination Notice [PDF] Language Assistance [PDF] Report Fraud Sitemap

Disclaimer

Individual and family medical and dental insurance plans are insured by Cigna Health and Life Insurance Company (CHLIC), Cigna HealthCare of Arizona, Inc., Cigna HealthCare of Illinois, Inc., and Cigna HealthCare of North Carolina, Inc. Group health insurance and health benefit plans are insured or administered by CHLIC, Connecticut General Life Insurance Company (CGLIC), or their affiliates (see a listing of the legal entities  that insure or administer group HMO, dental HMO, and other products or services in your state). Accidental Injury, Critical Illness, and Hospital Care plans or insurance policies are distributed exclusively by or through operating subsidiaries of Cigna Corporation, are administered by Cigna Health and Life Insurance Company, and are insured by either (i) Cigna Health and Life Insurance Company (Bloomfield, CT); (ii) Life Insurance Company of North America (“LINA”) (Philadelphia, PA); or (iii) New York Life Group Insurance Company of NY (“NYLGICNY”) (New York, NY), formerly known as Cigna Life Insurance Company of New York. The Cigna name, logo, and other Cigna marks are owned by Cigna Intellectual Property, Inc. LINA and NYLGICNY are not affiliates of Cigna.

All insurance policies and group benefit plans contain exclusions and limitations. For availability, costs and complete details of coverage, contact a licensed agent or Cigna sales representative. This website is not intended for residents of New Mexico.

Selecting these links will take you away from Cigna.com to another website, which may be a non-Cigna website. Cigna may not control the content or links of non-Cigna websites. Details