ertugliflozin and metformin

Skip to main navigation

Skip to footer

For Medicare For Providers For Brokers For Employers

Español

For Individuals & Families:

For Individuals & Families

Shop for Plans

Medical

Dental

Other Supplemental

Explore coverage through work

How to Buy Health Insurance

Types of Dental Insurance

Open Enrollment vs. Special Enrollment

See all topics

Shop for Medicare plans

Member Guide

Find a Doctor

Home

Knowledge Center

Wellness Library

ertugliflozin and metformin

Pronunciation: ER too gli FLOE zin and met FOR min

Brand: Segluromet

Segluromet

slide 1 of 4, Segluromet,

7.5 mg-1000 mg, oval, red, imprinted with 7.5/1000

slide 1 of 4

Segluromet

slide 2 of 4, Segluromet,

2.5 mg-500 mg, oval, pink, imprinted with 2.5/500

slide 2 of 4

Segluromet

slide 3 of 4, Segluromet,

7.5 mg-500 mg, oval, red, imprinted with 7.5/500

slide 3 of 4

Segluromet

slide 4 of 4, Segluromet,

2.5 mg-1000 mg, oval, pink, imprinted with 2.5/1000

slide 4 of 4

What is the most important information I should know about ertugliflozin and metformin?

You should not use this medicine if you have severe kidney disease, if you are on dialysis, or if you have diabetic ketoacidosis.

Ertugliflozin may increase your risk of lower leg amputation, especially if you have had a prior amputation, a foot ulcer, heart disease, circulation problems, or nerve damage.

Ertugliflozin can cause serious infections in the penis or vagina. Get medical help right away if you have burning, itching, odor, discharge, pain, tenderness, redness or swelling of the genital or rectal area, fever, or if you don't feel well.

You may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. Call your doctor or get emergency medical help if you have unusual muscle pain, trouble breathing, stomach pain, dizziness, feeling cold, or feeling very weak or tired.

What is ertugliflozin and metformin?

Ertugliflozin and metformin is a combination medicine used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. This medicine is not for treating type 1 diabetes.

Ertugliflozin and metformin may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking ertugliflozin and metformin?

You should not use this medicine if you are allergic to ertugliflozin or metformin, or if you have:

severe kidney disease (or if you are on dialysis); or
diabetic ketoacidosis (call your doctor for treatment).

If you need to have any type of x-ray or CT scan using a dye that is injected into your veins, you may need to temporarily stop taking ertugliflozin and metformin.

Ertugliflozin may increase your risk of lower leg amputation, especially if you have had a prior amputation, a foot ulcer, heart disease, circulation problems, or nerve damage.

Tell your doctor if you have ever had:

heart problems;
a diabetic foot ulcer or amputation;
circulation problems or nerve problems in your legs or feet;
liver or kidney disease;
high ketone levels in your blood or urine;
bladder infections or other urination problems;
low blood pressure;
problems with your pancreas, including surgery;
if you drink alcohol often; or
if you are on a low salt diet.

You may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. This may be more likely if you have other medical conditions, a severe infection, chronic alcoholism, or if you are 65 or older. Ask your doctor about your risk.

Follow your doctor's instructions about using this medicine if you are pregnant or you become pregnant. Controlling diabetes is very important during pregnancy, and having high blood sugar may cause complications in both the mother and the baby.

You should not use this medicine during the second or third trimester of pregnancy.

Metformin may stimulate ovulation in a premenopausal woman and may increase the risk of unintended pregnancy. Talk to your doctor about your risk.

You should not breastfeed while using this medicine.

Ertugliflozin and metformin is not approved for use by anyone younger than 18 years old.

How should I take ertugliflozin and metformin?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Ertugliflozin and metformin works best if you take it with food.

Call your doctor if you are sick with vomiting or diarrhea, if you consume less food or fluid than usual, or if you are sweating more than usual.

Your blood sugar will need to be checked often, and you may also need to test the level of ketones your urine. Ertugliflozin and metformin can cause life-threatening ketoacidosis (too much acid in the blood). Even if your blood sugar is normal, contact your doctor if a urine test shows that you have ketones in the urine.

You may have low blood sugar (hypoglycemia) and feel very hungry, dizzy, irritable, confused, anxious, or shaky. To quickly treat hypoglycemia, eat or drink a fast-acting source of sugar (fruit juice, hard candy, crackers, raisins, or non-diet soda).

Your doctor may prescribe a glucagon injection kit in case you have severe hypoglycemia. Be sure your family or close friends know how to give you this injection in an emergency.

Also watch for signs of high blood sugar (hyperglycemia) such as increased thirst or urination.

Blood sugar levels can be affected by stress, illness, surgery, exercise, alcohol use, or skipping meals. Ask your doctor before changing your dose or medication schedule.

This medicine can cause unusual results with certain lab tests. Tell any doctor who treats you that you are using ertugliflozin and metformin.

Ertugliflozin and metformin is only part of a complete treatment program that may also include diet, exercise, weight control, blood sugar testing, and special medical care. Follow your doctor's instructions very closely.

Your doctor may have you take extra vitamin B12. Take only the amount of vitamin B12 that your doctor has prescribed.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can cause lactic acidosis.

What should I avoid while taking ertugliflozin and metformin?

Avoid drinking alcohol. It lowers blood sugar and may increase your risk of lactic acidosis.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.

What are the possible side effects of ertugliflozin and metformin?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Seek medical attention right away if you have signs of a genital infection (penis or vagina): burning, itching, odor, discharge, pain, tenderness, redness or swelling of the genital or rectal area, fever, not feeling well. These symptoms may get worse quickly.

Call your doctor at once if you have:

new pain, tenderness, sores, ulcers, or infections in your legs or feet;
little or no urination;
lactic acidosis --unusual muscle pain, trouble breathing, stomach pain, vomiting, irregular heart rate, dizziness, feeling cold, or feeling very weak or tired;
ketoacidosis (too much acid in the blood) --nausea, vomiting, stomach pain, confusion, unusual drowsiness, or trouble breathing;
dehydration symptoms --dizziness, weakness, feeling light-headed (like you might pass out); or
signs of a bladder infection --pain or burning when you urinate, increased urination, blood in your urine, fever, pain in your pelvis or back.

Some side effects may be more likely to occur in older adults.

Common side effects may include:

genital yeast infection;
stomach discomfort;
nausea, vomiting, diarrhea, gas;
headache, weakness; or
urinating more than usual.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect ertugliflozin and metformin?

When you start or stop taking ertugliflozin and metformin, your doctor may need to adjust the doses of any other diabetes medicines you use on a regular basis.

Other drugs may affect ertugliflozin and metformin, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Where can I get more information?

Your pharmacist can provide more information about ertugliflozin and metformin.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2023 Cerner Multum, Inc. Version: 4.02. Revision date: 3/31/2020.

Your use of the content provided in this service indicates that you have read, understood and agree to the End-User License Agreement, which can be accessed by End-User License Agreement, which can be accessed by clicking on this link.

This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.

Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.

<cipublic-spinner variant="large"><span>Loading…</span></cipublic-spinner>

Page Footer

I want to...

Get an ID card

File a claim

View my claims and EOBs

Check coverage under my plan

See prescription drug list

Find an in-network doctor, dentist, or facility

Find a form

Find 1095-B tax form information

View the Cigna Glossary

Contact Cigna

Audiences

Individuals and Families

Medicare

Employers

Brokers

Providers

Secure Member Sites

myCigna member portal

Health Care Provider portal

Cigna for Employers

Client Resource Portal

Cigna for Brokers

The Cigna Group Information

About The Cigna Group

Company Profile

Careers

Newsroom

Investors

Suppliers

The Cigna Group

Third Party Administrators

International

Evernorth

Privacy

Legal

Product Disclosures

Cigna Company Names

Customer Rights

Accessibility

Non-Discrimination Notice

Language Assistance [PDF]

Report Fraud

Sitemap

Disclaimer

Individual and family medical and dental insurance plans are insured by Cigna Health and Life Insurance Company (CHLIC), Cigna HealthCare of Arizona, Inc., Cigna HealthCare of Illinois, Inc., Cigna HealthCare of Georgia, Inc., Cigna HealthCare of North Carolina, Inc., Cigna HealthCare of South Carolina, Inc., and Cigna HealthCare of Texas, Inc. Group health insurance and health benefit plans are insured or administered by CHLIC, Connecticut General Life Insurance Company (CGLIC), or their affiliates (see a listing of the legal entities that insure or administer group HMO, dental HMO, and other products or services in your state). Accidental Injury, Critical Illness, and Hospital Care plans or insurance policies are distributed exclusively by or through operating subsidiaries of Cigna Corporation, are administered by Cigna Health and Life Insurance Company, and are insured by either (i) Cigna Health and Life Insurance Company (Bloomfield, CT); (ii) Life Insurance Company of North America (“LINA”) (Philadelphia, PA); or (iii) New York Life Group Insurance Company of NY (“NYLGICNY”) (New York, NY), formerly known as Cigna Life Insurance Company of New York. The Cigna name, logo, and other Cigna marks are owned by Cigna Intellectual Property, Inc. LINA and NYLGICNY are not affiliates of Cigna.

All insurance policies and group benefit plans contain exclusions and limitations. For availability, costs and complete details of coverage, contact a licensed agent or Cigna sales representative. This website is not intended for residents of New Mexico.

Selecting these links will take you away from Cigna.com to another website, which may be a non-Cigna website. Cigna may not control the content or links of non-Cigna websites. Details

Shop for Plans

Shop for your own coverage

Plans through your employer

Learn

Looking for Medicare coverage?

ertugliflozin and metformin

Segluromet

Segluromet

Segluromet

Segluromet

What is the most important information I should know about ertugliflozin and metformin?

What is ertugliflozin and metformin?

What should I discuss with my healthcare provider before taking ertugliflozin and metformin?

How should I take ertugliflozin and metformin?

What happens if I miss a dose?

What happens if I overdose?

What should I avoid while taking ertugliflozin and metformin?

What are the possible side effects of ertugliflozin and metformin?

What other drugs will affect ertugliflozin and metformin?

Where can I get more information?

Page Footer

I want to...

Audiences

Secure Member Sites

The Cigna Group Information

Disclaimer