Skip to main navigation Skip to main content Skip to footer For Medicare For Providers For Brokers For Employers Español For Individuals & Families: For Individuals & Families Medical Dental Other Supplemental Explore coverage through work How to Buy Health Insurance Types of Dental Insurance Open Enrollment vs. Special Enrollment See all topics Shop for Medicare plans Member Guide Find a Doctor Log in to myCigna
Home Knowledge Center Wellness Library estramustine

estramustine

Pronunciation: ES tra MUS teen

Brand: Emcyt

Emcyt

slide 1 of 1, Emcyt,

140 mg, capsule, white, imprinted with Pharmacia & Upjohn, EMCYT 140mg

Image of Emcyt
slide 1 of 1
What is the most important information I should know about estramustine?

What is the most important information I should know about estramustine?

You should not use this medicine if you have a blood clot, swelling of a vein caused by a blood clot, or if you have ever had an allergic reaction to estradiol or nitrogen mustard.

What is estramustine?

What is estramustine?

Estramustine is used to treat metastatic or progressive prostate cancer.

Estramustine may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking estramustine?

What should I discuss with my healthcare provider before taking estramustine?

You should not use estramustine if you are allergic to estradiol or to nitrogen mustard.

You may not be able to use this medicine if you have a blood clot or swelling of a vein caused by a blood clot.

Tell your doctor if you have ever had:

  • a blood clot, stroke, or heart attack;
  • diabetes;
  • high blood pressure (hypertension);
  • heart disease or coronary artery disease (atherosclerosis);
  • congestive heart failure;
  • migraine headaches;
  • epilepsy or other seizure disorder;
  • low or high levels of calcium in your blood;
  • liver disease;
  • kidney disease; or
  • a bone disorder such as osteoporosis or Paget's disease.

If a man fathers a baby while using estramustine, the baby may have birth defects. Use condoms to prevent pregnancy during your treatment. Ask your doctor how long you should continue using condoms after you stop taking estramustine.

How should I take estramustine?

How should I take estramustine?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Take estramustine on an empty stomach, at least 1 hour before or 2 hours after a meal.

Take this medicine with water, not with milk or other dairy products.

Estramustine doses are based on weight (especially in children and teenagers). Your dose needs may change if you gain or lose weight.

It may take up to 90 days before you receive the full benefit of taking estramustine. Your doctor will determine how long to treat you.

You may need frequent blood tests. Your blood pressure will also need to be checked often.

This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using estramustine.

Store in the refrigerator, do not freeze.

What happens if I miss a dose?

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking estramustine?

What should I avoid while taking estramustine?

Do not take estramustine with milk, milk products, calcium supplements, or calcium-rich foods such as ice cream, yogurt, broccoli, and others.

Avoid using antacids or vitamin/mineral supplements that contain calcium. Calcium can make it harder for your body to absorb estramustine.

What are the possible side effects of estramustine?

What are the possible side effects of estramustine?

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using estramustine and call your doctor at once if you have:

  • heart problems --shortness of breath (even with mild exertion), swelling, rapid weight gain, chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating;
  • signs of a stroke --sudden numbness or weakness (especially on one side of the body), severe headache, slurred speech, balance problems;
  • signs of a blood clot in the lung --chest pain, sudden cough, wheezing, rapid breathing, coughing up blood; or
  • signs of a blood clot deep in the body --swelling, warmth, or redness in an arm or leg.

Common side effects may include:

  • breast swelling or tenderness;
  • impotence;
  • nausea, diarrhea, upset stomach;
  • swelling, trouble breathing;
  • leg cramps; or
  • abnormal liver function tests.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect estramustine?

What other drugs will affect estramustine?

Other drugs may affect estramustine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Where can I get more information?

Where can I get more information?

Your doctor or pharmacist can provide more information about estramustine.

This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.

Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.

<cipublic-spinner variant="large"><span>Loading…</span></cipublic-spinner>

Page Footer

I want to...

Get an ID card File a claim View my claims and EOBs Check coverage under my plan See prescription drug list Find an in-network doctor, dentist, or facility Find a form Find 1095-B tax form information View the Cigna Glossary Contact Cigna

Audiences

Individuals and Families Medicare Employers Brokers Providers

Secure Member Sites

myCigna member portal Health Care Provider portal Cigna for Employers Client Resource Portal Cigna for Brokers

Cigna Company Information

About Cigna Company Profile Careers Newsroom Investors Suppliers Third Party Administrators International Evernorth

 Cigna. All rights reserved.

Privacy Legal Product Disclosures Cigna Company Names Customer Rights Accessibility Non-Discrimination Notice [PDF] Language Assistance [PDF] Report Fraud Sitemap

Disclaimer

Individual and family medical and dental insurance plans are insured by Cigna Health and Life Insurance Company (CHLIC), Cigna HealthCare of Arizona, Inc., Cigna HealthCare of Illinois, Inc., and Cigna HealthCare of North Carolina, Inc. Group health insurance and health benefit plans are insured or administered by CHLIC, Connecticut General Life Insurance Company (CGLIC), or their affiliates (see a listing of the legal entities  that insure or administer group HMO, dental HMO, and other products or services in your state). Accidental Injury, Critical Illness, and Hospital Care plans or insurance policies are distributed exclusively by or through operating subsidiaries of Cigna Corporation, are administered by Cigna Health and Life Insurance Company, and are insured by either (i) Cigna Health and Life Insurance Company (Bloomfield, CT); (ii) Life Insurance Company of North America (“LINA”) (Philadelphia, PA); or (iii) New York Life Group Insurance Company of NY (“NYLGICNY”) (New York, NY), formerly known as Cigna Life Insurance Company of New York. The Cigna name, logo, and other Cigna marks are owned by Cigna Intellectual Property, Inc. LINA and NYLGICNY are not affiliates of Cigna.

All insurance policies and group benefit plans contain exclusions and limitations. For availability, costs and complete details of coverage, contact a licensed agent or Cigna sales representative. This website is not intended for residents of New Mexico.

Selecting these links will take you away from Cigna.com to another website, which may be a non-Cigna website. Cigna may not control the content or links of non-Cigna websites. Details