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Home Knowledge Center Wellness Library Estrogens, Conjugated (USP) Vaginal Cream (ESTROGENS CREAM - VAGINAL)

Estrogens, Conjugated (USP) Vaginal Cream (ESTROGENS CREAM - VAGINAL)

This medicine is used for the following purposes:

  • endocrine disorder
  • labial adhesion
  • menopausal symptoms

Brand Name(s): Premarin

Generic Name: Estrogens, Conjugated

Instructions

Instructions

This medicine is for use in the vagina. DO NOT take this medicine by mouth.

Use the medicine each night at bedtime.

Use only the applicator that is supplied with the medicine to insert the cream into the vagina.

Keep the medicine at room temperature. Avoid heat and direct light.

This medicine may cause dark patches to appear on your face. Avoid sunlight and use sunscreen lotion to minimize further darkening of these skin patches.

This medicine can make you sensitive to the sun. Use sunscreen or protective clothing when in sun.

It is important that you keep taking each dose of this medicine on time even if you are feeling well.

If you forget to take a dose on time, take it as soon as you remember. If it is almost time for the next dose, do not take the missed dose. Return to your normal schedule. Do not take 2 doses at one time.

Do not use tampons or douche on the days that you are using the medicine.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

Tell your doctor if symptoms do not get better or if they get worse.

This medicine may affect your blood sugar levels. If you have diabetes, talk to your doctor before changing the dose of your diabetes medicine.

Do not share this medicine with anyone who has not been prescribed this medicine.

Cautions

Cautions

Some patients taking this medicine have experienced serious side effects. Please speak with your doctor to understand the risks and benefits associated with this medicine.

This medicine is associated with an increased risk for serious blood clots. Speak with your doctor about the benefits and risks from using this medicine.

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

Do not use the medication any more than instructed.

Avoid smoking while on this medicine. Smoking may increase your risk for stroke, heart attack, blood clots, high blood pressure, and other diseases of the heart and blood vessels.

Ask your doctor how to do a breast self-exam. Check monthly. Report any changes to your doctor.

Talk to your doctor about getting a complete physical exam every year while on this medicine.

Tell the doctor or pharmacist if you are pregnant, planning to be pregnant, or breastfeeding.

Do not use this medicine if you are pregnant. If you become pregnant, contact your doctor immediately.

Side Effects

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

  • bloating
  • breast pain or swelling
  • headaches
  • brown colored patches on the face
  • nausea and vomiting
  • stomach upset or abdominal pain
  • weight gain

Call your doctor or get medical help right away if you notice any of these more serious side effects:

  • breast lumps
  • increased risk of cancer
  • chest or jaw pain
  • changes in memory, mood, or thinking
  • depression or feeling sad
  • swelling of the legs, feet, and hands
  • fainting
  • severe or persistent headache
  • sudden leg pain, swelling, warmth or redness
  • signs of liver damage (such as yellowing of eye or skin, dark urine, or unusual tiredness)
  • shortness of breath
  • symptoms of stroke (such as one-sided weakness, slurred speech, confusion)
  • persistent or unusual thirst
  • increased urinary frequency
  • cramping of the uterus or bleeding from the vagina
  • vaginal bleeding or spotting between periods
  • vaginal itching or discharge
  • blurring or changes of vision
  • severe or persistent vomiting

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.

Please speak with your doctor, nurse, or pharmacist if you have any questions about this medicine.

This information does not replace the advice of a doctor. Ignite Healthwise, LLC, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.

Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Ignite Healthwise, LLC.

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