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Home Knowledge Center Wellness Library fluphenazine (oral/injection)

fluphenazine (oral/injection)

Pronunciation: floo FEN a zeen

Brand: Permitil, Prolixin, Prolixin Decanoate

FluPHENAZine Hydrochloride

slide 1 of 14, FluPHENAZine Hydrochloride,

1 mg, triangular, white, imprinted with 4, M

Image of FluPHENAZine Hydrochloride
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FluPHENAZine Hydrochloride

slide 2 of 14, FluPHENAZine Hydrochloride,

2.5 mg, triangular, yellow, imprinted with 9, M

Image of FluPHENAZine Hydrochloride
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FluPHENAZine Hydrochloride

slide 3 of 14, FluPHENAZine Hydrochloride,

5 mg, triangular, green, imprinted with 74, M

Image of FluPHENAZine Hydrochloride
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FluPHENAZine Hydrochloride

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10 mg, triangular, orange, imprinted with M, 97

Image of FluPHENAZine Hydrochloride
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FluPHENAZine Hydrochloride

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1 mg, round, white, imprinted with LCI, 1788

Image of FluPHENAZine Hydrochloride
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FluPHENAZine Hydrochloride

slide 6 of 14, FluPHENAZine Hydrochloride,

2.5 mg, round, blue, imprinted with LCI, 1789

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FluPHENAZine Hydrochloride

slide 7 of 14, FluPHENAZine Hydrochloride,

5 mg, round, pink, imprinted with LCI, 1790

Image of FluPHENAZine Hydrochloride
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FluPHENAZine Hydrochloride

slide 8 of 14, FluPHENAZine Hydrochloride,

10 mg, round, orange, imprinted with LCI, 1791

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FluPHENAZine Hydrochloride

slide 9 of 14, FluPHENAZine Hydrochloride,

1 mg, round, brown, imprinted with GG97

Image of FluPHENAZine Hydrochloride
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FluPHENAZine Hydrochloride

slide 10 of 14, FluPHENAZine Hydrochloride,

10 mg, triangular, orange, imprinted with 97, M

Image of FluPHENAZine Hydrochloride
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FluPHENAZine Hydrochloride

slide 11 of 14, FluPHENAZine Hydrochloride,

10 mg, round, orange, imprinted with LCI, 1791

Image of FluPHENAZine Hydrochloride
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FluPHENAZine Hydrochloride

slide 12 of 14, FluPHENAZine Hydrochloride,

1 mg, round, white, imprinted with LCI, 1788

Image of FluPHENAZine Hydrochloride
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FluPHENAZine Hydrochloride

slide 13 of 14, FluPHENAZine Hydrochloride,

2.5 mg, round, blue, imprinted with LCI, 1789

Image of FluPHENAZine Hydrochloride
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FluPHENAZine Hydrochloride

slide 14 of 14, FluPHENAZine Hydrochloride,

5 mg, round, pink, imprinted with LCI, 1790

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What is the most important information I should know about fluphenazine?

What is the most important information I should know about fluphenazine?

You should not use fluphenazine if you have liver disease, brain damage, severe depression, a blood cell disorder, or if you are also using large amounts of alcohol or medicines that make you sleepy.

Fluphenazine is not approved for use in older adults with dementia-related psychosis.

Call your doctor at once if you have uncontrollable movements of your eyes, lips, tongue, face, arms, or legs. These could be early signs of dangerous side effects.

What is fluphenazine?

What is fluphenazine?

Fluphenazine is a phenothiazine (FEEN-oh-THYE-a-zeen) antipsychotic medicine that is used to treat psychotic disorders such as schizophrenia.

Fluphenazine may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before using fluphenazine?

What should I discuss with my healthcare provider before using fluphenazine?

You should not use this medicine if you are allergic to fluphenazine or other phenothiazines (chlorpromazine, perphenazine, prochlorperazine, promethazine, thioridazine, trifluoperazine), or if you have:

  • liver disease;
  • brain damage;
  • severe depression; or
  • a blood cell disorder (such as low platelets or low red or white blood cell counts).

Do not use fluphenazine if you have recently used large amounts of alcohol or medicine that makes you sleepy.

Fluphenazine may increase the risk of death in older adults with dementia-related psychosis and is not approved for this use.

Tell your doctor if you have ever had:

  • heart problems;
  • liver or kidney disease;
  • low white blood cell (WBC) counts;
  • breast cancer;
  • glaucoma;
  • Parkinson's disease;
  • seizures; or
  • pheochromocytoma (tumor of the adrenal gland).

Tell your doctor if you will be exposed to extreme heat or cold, or to insecticide poisons while you are using fluphenazine.

Fluphenazine is not approved for use by anyone younger than 12 years old.

Using antipsychotic medicine in the last 3 months of pregnancy may cause breathing problems, feeding problems, or withdrawal symptoms in the newborn. If you get pregnant, tell your doctor right away. Do not stop using fluphenazine without your doctor's advice.

Fluphenazine may cause false results on a pregnancy test. Tell your doctor if you think you might be pregnant.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

How should I use fluphenazine?

How should I use fluphenazine?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Fluphenazine oral is taken by mouth.

Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

Fluphenazine oral concentrate solution must be mixed with at least 2 ounces (1/4 cup) of a liquid such as milk, tomato juice, fruit juice (but not apple juice), or a soft drink that does not contain caffeine.

Fluphenazine injection is injected into a muscle or under the skin by a healthcare provider. Fluphenazine is usually given by injection only after you have taken the medicine by mouth for a certain period of time.

Fluphenazine injection stays in your body longer than the oral form, and the injections are not given daily. Follow your doctor's dosing instructions very carefully.

You may need frequent medical tests. Your next dose may be delayed based on the results.

If you need surgery, tell the surgeon ahead of time that you are using fluphenazine.

Do not stop using fluphenazine suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using this medicine.

Store at room temperature away from moisture, heat, and light. Do not allow liquid medicine to freeze.

What happens if I miss a dose?

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

Call your doctor for instructions if you miss an appointment for your fluphenazine injection.

What happens if I overdose?

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using fluphenazine?

What should I avoid while using fluphenazine?

Avoid driving or hazardous activity until you know how this medicine will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.

Drinking alcohol with this medicine can cause side effects.

Fluphenazine could make you sunburn more easily. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

What are the possible side effects of fluphenazine?

What are the possible side effects of fluphenazine?

Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

High doses or long-term use of fluphenazine can cause a serious movement disorder that may not be reversible. The longer you use fluphenazine, the more likely you are to develop this disorder, especially if you are an older adult.

Call your doctor at once if you have:

  • uncontrolled muscle movements in your face (chewing, lip smacking, frowning, tongue movement, blinking or eye movement);
  • extreme drowsiness or light-headed feeling (like you might pass out);
  • strange dreams, or if you feel restless or excited;
  • blurred vision, tunnel vision, eye pain, or seeing halos around lights;
  • painful or difficult urination;
  • severe constipation, stomach pain, bloating;
  • jaundice (yellowing of the skin or eyes);
  • a seizure; or
  • low white blood cell counts --fever, chills, mouth sores, skin sores, sore throat, cough, trouble breathing, feeling light-headed.

Common side effects may include:

  • drowsiness, headache, blurred vision;
  • problems with balance or muscle movement;
  • nausea, loss of appetite, constipation;
  • swelling, weight changes;
  • stuffy nose, dry mouth, or drooling;
  • increased sweating or urination;
  • breast swelling or tenderness; or
  • impotence, trouble having an orgasm.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect fluphenazine?

What other drugs will affect fluphenazine?

Using fluphenazine with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.

Other drugs may affect fluphenazine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Where can I get more information?

Where can I get more information?

Your pharmacist can provide more information about fluphenazine.

This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.

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