Skip to main navigation Skip to main content Skip to footer For Medicare For Providers For Brokers For Employers Español For Individuals & Families: For Individuals & Families Medical Dental Other Supplemental Explore coverage through work How to Buy Health Insurance Types of Dental Insurance Open Enrollment vs. Special Enrollment See all topics Shop for Medicare plans Member Guide Find a Doctor Log in to myCigna
Home Knowledge Center Wellness Library fosdenopterin


Pronunciation: FOS den OP ter in

Brand: Nulibry

What is the most important information I should know about fosdenopterin?

What is the most important information I should know about fosdenopterin?

Follow all directions on your medicine label and package. Tell each of your child's healthcare providers about all the child's medical conditions, allergies, and medicines.

What is fosdenopterin?

What is fosdenopterin?

Fosdenopterin is used to reduce the risk of death in children with molybdenum cofactor deficiency (MoCD) Type A.

Molybdenum (moe-LIB-den-um) cofactor deficiency is a rare condition in newborn babies that affects brain function and gets worse over time. Babies with MoCD begin to show symptoms within a week after birth, and this condition can lead to severe developmental delays and life-threatening health problems.

Fosdenopterin may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before using fosdenopterin?

What should I discuss with my healthcare provider before using fosdenopterin?

Your doctor will perform a genetic test to make sure your baby has MoCD.

Fosdenopterin is sometimes given before genetic testing results are available. Treatment will be stopped if the test shows that your baby does not have MoCD.

How should I use fosdenopterin?

How should I use fosdenopterin?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your child's dose. Use the medicine exactly as directed.

Fosdenopterin is given using an infusion pump attached to a catheter placed into a vein. A healthcare provider can teach you how to properly use the infusion pump by yourself.

You may need to keep a diary of the dates and times for each dose you give to your child. You may also need to record information about the specific vials and amounts of fosdenopterin you use each time. Take this information with you every time you take your child t the doctor.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you don't understand all instructions.

Fosdenopterin must be mixed with a liquid (diluent) before using it. When using injections by yourself, be sure you understand how to properly mix and store the medicine.

Do not shake the mixed medicine.

Prepare an injection only when you are ready to give it. Each infusion should be finished within 4 hours after you mixed the medicine with the diluent.

Do not use if the medicine looks cloudy, has changed colors, or has particles in it. Call your pharmacist for new medicine.

Fosdenopterin doses are based on weight. Your child's dose needs may change if the child gains or loses weight.

Store unmixed fosdenopterin in a freezer. Keep each vial in its original carton and protect from light.

Take the medicine out of the freezer and let it reach room temperature for 30 minutes before mixing with the diluent. You may also warm the medicine in your hands for 3 to 5 minutes. Do not heat the medicine.

You may store mixed medicine in the refrigerator or at room temperature. If stored in a refrigerator, allow the mixture to reach room temperature before giving the injection. Complete the injection within 4 hours after mixing the medicine.

What happens if I miss a dose?

What happens if I miss a dose?

Give the medicine as soon as you can, then give the next injection at least 6 hours later and return to the regular daily injection schedule. Do not give two doses at one time.

What happens if I overdose?

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using fosdenopterin?

What should I avoid while using fosdenopterin?

Fosdenopterin could make your child sunburn more easily. Avoid sunlight or tanning beds. Be sure the child wears protective clothing, a hat, and sunglasses while outdoors. Also apply sunscreen (SPF 30 or higher) if your child is at least 6 months old.

What are the possible side effects of fosdenopterin?

What are the possible side effects of fosdenopterin?

Get emergency medical help if your child has signs of an allergic reaction: hives; difficult breathing; swelling of the face, lips, tongue, or throat.

Call your doctor at once if your child has:

  • a fever;
  • severe or ongoing vomiting or diarrhea;
  • bruising, swelling, discomfort, or skin changes around the catheter;
  • cough with mucus, trouble breathing;
  • a seizure; or
  • signs of an ear infection --fever, ear pain, drainage from the ear, fussiness.

Seek emergency medical attention if your child has a skin rash or symptoms of serious sunburn such as skin redness, burning, or blisters.

Common side effects may include:

  • problems with the catheter or IV line;
  • fever;
  • vomiting, diarrhea; or
  • cold symptoms such as stuffy nose, sneezing, cough.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect fosdenopterin?

What other drugs will affect fosdenopterin?

Other drugs may affect fosdenopterin, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your child's current medicines and any medicines the child starts or stops using.

Where can I get more information?

Where can I get more information?

Your pharmacist can provide more information about fosdenopterin.

This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.

Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.

<cipublic-spinner variant="large"><span>Loading…</span></cipublic-spinner>

Page Footer

I want to...

Get an ID card File a claim View my claims and EOBs Check coverage under my plan See prescription drug list Find an in-network doctor, dentist, or facility Find a form Find 1095-B tax form information View the Cigna Glossary Contact Cigna


Individuals and Families Medicare Employers Brokers Providers

Secure Member Sites

myCigna member portal Health Care Provider portal Cigna for Employers Client Resource Portal Cigna for Brokers

The Cigna Group Information

About The Cigna Group Company Profile Careers Newsroom Investors Suppliers The Cigna Group Third Party Administrators International Evernorth

 Cigna. All rights reserved.

Privacy Legal Product Disclosures Cigna Company Names Customer Rights Accessibility Non-Discrimination Notice Language Assistance [PDF] Report Fraud Sitemap


Individual and family medical and dental insurance plans are insured by Cigna Health and Life Insurance Company (CHLIC), Cigna HealthCare of Arizona, Inc., Cigna HealthCare of Illinois, Inc., Cigna HealthCare of Georgia, Inc., Cigna HealthCare of North Carolina, Inc., Cigna HealthCare of South Carolina, Inc., and Cigna HealthCare of Texas, Inc. Group health insurance and health benefit plans are insured or administered by CHLIC, Connecticut General Life Insurance Company (CGLIC), or their affiliates (see a listing of the legal entities that insure or administer group HMO, dental HMO, and other products or services in your state). Accidental Injury, Critical Illness, and Hospital Care plans or insurance policies are distributed exclusively by or through operating subsidiaries of Cigna Corporation, are administered by Cigna Health and Life Insurance Company, and are insured by either (i) Cigna Health and Life Insurance Company (Bloomfield, CT); (ii) Life Insurance Company of North America (“LINA”) (Philadelphia, PA); or (iii) New York Life Group Insurance Company of NY (“NYLGICNY”) (New York, NY), formerly known as Cigna Life Insurance Company of New York. The Cigna name, logo, and other Cigna marks are owned by Cigna Intellectual Property, Inc. LINA and NYLGICNY are not affiliates of Cigna.

All insurance policies and group benefit plans contain exclusions and limitations. For availability, costs and complete details of coverage, contact a licensed agent or Cigna sales representative. This website is not intended for residents of New Mexico.

Selecting these links will take you away from to another website, which may be a non-Cigna website. Cigna may not control the content or links of non-Cigna websites. Details