Skip to main navigation Skip to main content Skip to footer For Medicare For Providers For Brokers For Employers Español For Individuals & Families: For Individuals & Families Medical Dental Other Supplemental Explore coverage through work How to Buy Health Insurance Types of Dental Insurance Open Enrollment vs. Special Enrollment See all topics Shop for Medicare plans Member Guide Find a Doctor Log in to myCigna
Home Knowledge Center Wellness Library hydrochlorothiazide and losartan

hydrochlorothiazide and losartan

Pronunciation: HYE droe KLOR oh THYE a zide and loe SAR tan

Brand: Hyzaar

Hyzaar

slide 1 of 26, Hyzaar,

12.5 mg-100 mg, oval, white, imprinted with 745

Image of Hyzaar
slide 1 of 26

Hyzaar

slide 2 of 26, Hyzaar,

25 mg-100 mg, oval, yellow, imprinted with 747

Image of Hyzaar
slide 2 of 26

Hydrochlorothiazide-Losartan

slide 3 of 26, Hydrochlorothiazide-Losartan,

12.5 mg-50 mg, oval, yellow, imprinted with 93, 7367

Image of Hydrochlorothiazide-Losartan
slide 3 of 26

Hydrochlorothiazide-Losartan

slide 4 of 26, Hydrochlorothiazide-Losartan,

25 mg-100 mg, oval, yellow, imprinted with 93, 7368

Image of Hydrochlorothiazide-Losartan
slide 4 of 26

Hydrochlorothiazide-Losartan

slide 5 of 26, Hydrochlorothiazide-Losartan,

12.5 mg-100 mg, oval, white, imprinted with 93, 7369

Image of Hydrochlorothiazide-Losartan
slide 5 of 26

Hydrochlorothiazide-Losartan

slide 6 of 26, Hydrochlorothiazide-Losartan,

12.5 mg-100 mg, round, white, imprinted with SZ 309

Image of Hydrochlorothiazide-Losartan
slide 6 of 26

Hydrochlorothiazide-Losartan

slide 7 of 26, Hydrochlorothiazide-Losartan,

12.5 mg-50 mg, round, white, imprinted with SZ 349

Image of Hydrochlorothiazide-Losartan
slide 7 of 26

Hydrochlorothiazide-Losartan

slide 8 of 26, Hydrochlorothiazide-Losartan,

25 mg-100 mg, round, white, imprinted with SZ 390

Image of Hydrochlorothiazide-Losartan
slide 8 of 26

Hydrochlorothiazide-Losartan

slide 9 of 26, Hydrochlorothiazide-Losartan,

12.5 mg-50 mg, oval, yellow, imprinted with 717

Image of Hydrochlorothiazide-Losartan
slide 9 of 26

Hydrochlorothiazide-Losartan

slide 10 of 26, Hydrochlorothiazide-Losartan,

12.5 mg-100 mg, oval, white, imprinted with 745

Image of Hydrochlorothiazide-Losartan
slide 10 of 26

Hydrochlorothiazide-Losartan

slide 11 of 26, Hydrochlorothiazide-Losartan,

25 mg-100 mg, oval, yellow, imprinted with 747

Image of Hydrochlorothiazide-Losartan
slide 11 of 26

Hydrochlorothiazide-Losartan

slide 12 of 26, Hydrochlorothiazide-Losartan,

12.5 mg-50 mg, oval, yellow, imprinted with 116

Image of Hydrochlorothiazide-Losartan
slide 12 of 26

Hydrochlorothiazide-Losartan

slide 13 of 26, Hydrochlorothiazide-Losartan,

25 mg-100 mg, oval, yellow, imprinted with 1118

Image of Hydrochlorothiazide-Losartan
slide 13 of 26

Hydrochlorothiazide-Losartan

slide 14 of 26, Hydrochlorothiazide-Losartan,

12.5 mg-100 mg, oval, white, imprinted with F, 74

Image of Hydrochlorothiazide-Losartan
slide 14 of 26

Hydrochlorothiazide-Losartan

slide 15 of 26, Hydrochlorothiazide-Losartan,

25 mg-100 mg, oval, yellow, imprinted with E, 49

Image of Hydrochlorothiazide-Losartan
slide 15 of 26

Hydrochlorothiazide-Losartan

slide 16 of 26, Hydrochlorothiazide-Losartan,

12.5 mg-50 mg, oval, yellow, imprinted with E, 48

Image of Hydrochlorothiazide-Losartan
slide 16 of 26

Hydrochlorothiazide-Losartan

slide 17 of 26, Hydrochlorothiazide-Losartan,

12.5 mg-100 mg, oval, white, imprinted with LU, M42

Image of Hydrochlorothiazide-Losartan
slide 17 of 26

Hydrochlorothiazide-Losartan

slide 18 of 26, Hydrochlorothiazide-Losartan,

12.5 mg-50 mg, oblong, white, imprinted with ZD18

Image of Hydrochlorothiazide-Losartan
slide 18 of 26

Hydrochlorothiazide-Losartan

slide 19 of 26, Hydrochlorothiazide-Losartan,

25 mg-100 mg, oblong, white, imprinted with ZD19

Image of Hydrochlorothiazide-Losartan
slide 19 of 26

Hyzaar

slide 20 of 26, Hyzaar,

12.5 mg-50 mg, oval, yellow, imprinted with 717

Image of Hyzaar
slide 20 of 26

Hyzaar

slide 21 of 26, Hyzaar,

12.5 mg-100 mg, oval, white, imprinted with 745

Image of Hyzaar
slide 21 of 26

Hyzaar

slide 22 of 26, Hyzaar,

25 mg-100 mg, oval, yellow, imprinted with 747

Image of Hyzaar
slide 22 of 26

Hydrochlorothiazide-Losartan

slide 23 of 26, Hydrochlorothiazide-Losartan,

25 mg-100 mg, oval, yellow, imprinted with C, 339

Image of Hydrochlorothiazide-Losartan
slide 23 of 26

Hydrochlorothiazide-Losartan

slide 24 of 26, Hydrochlorothiazide-Losartan,

12.5 mg-100 mg, round, white, imprinted with 54, 931

Image of Hydrochlorothiazide-Losartan
slide 24 of 26

Hydrochlorothiazide-Losartan

slide 25 of 26, Hydrochlorothiazide-Losartan,

25 mg-100 mg, round, yellow, imprinted with 54 557

Image of Hydrochlorothiazide-Losartan
slide 25 of 26

Hydrochlorothiazide-Losartan

slide 26 of 26, Hydrochlorothiazide-Losartan,

12.5 mg-50 mg, round, yellow, imprinted with 54 717

Image of Hydrochlorothiazide-Losartan
slide 26 of 26
What is the most important information I should know about hydrochlorothiazide and losartan?

What is the most important information I should know about hydrochlorothiazide and losartan?

You should not use this medicine if you are unable to urinate.

Do not use if you are pregnant. Stop using the medicine and tell your doctor right away if you become pregnant.

If you have diabetes, do not use hydrochlorothiazide and losartan together with any medication that contains aliskiren (a blood pressure medicine).

What is hydrochlorothiazide and losartan?

What is hydrochlorothiazide and losartan?

Hydrochlorothiazide is a diuretic (water pill). Losartan is an angiotensin II receptor antagonist (sometimes called an ARB blocker).

Hydrochlorothiazide and losartan is a combination medicine used to treat high blood pressure (hypertension). It is also used to lower the risk of stroke in certain people with heart disease.

Hydrochlorothiazide and losartan may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking hydrochlorothiazide and losartan?

What should I discuss with my healthcare provider before taking hydrochlorothiazide and losartan?

You should not use this medicine if you are allergic to hydrochlorothiazide or losartan, if you are unable to urinate.

If you have diabetes, do not use hydrochlorothiazide and losartan together with any medication that contains aliskiren (a blood pressure medicine).

You may also need to avoid taking hydrochlorothiazide and losartan with aliskiren if you have kidney disease.

Tell your doctor if you have ever had:

  • lupus;
  • liver or kidney disease;
  • asthma or allergies;
  • diabetes;
  • gout;
  • congestive heart failure;
  • glaucoma;
  • low or high levels of potassium in your blood;
  • high cholesterol or triglyceride levels; or
  • an allergy to penicillin or sulfa drugs.

Do not use if you are pregnant. Stop using the medicine and tell your doctor right away if you become pregnant. Hydrochlorothiazide and losartan can cause injury or death to the unborn baby if you take the medicine during your second or third trimester.

You should not breastfeed while using this medicine.

Hydrochlorothiazide and losartan is not approved for use by anyone younger than 18 years old.

How should I take hydrochlorothiazide and losartan?

How should I take hydrochlorothiazide and losartan?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Your blood pressure will need to be checked often.

Call your doctor if you are sick with vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking this medicine. This can lead to very low blood pressure, a serious electrolyte imbalance, or kidney failure.

If you need surgery or medical tests, tell the surgeon ahead of time that you are using hydrochlorothiazide and losartan.

If you have high blood pressure, keep using this medicine even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life.

Store at room temperature away from moisture, heat, and light.

What happens if I miss a dose?

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking hydrochlorothiazide and losartan?

What should I avoid while taking hydrochlorothiazide and losartan?

Hydrochlorothiazide may increase your risk of skin cancer. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors. Your doctor may want you to have skin examinations on a regular basis.

Do not use potassium supplements or salt substitutes, unless your doctor has told you to.

Drinking alcohol can further lower your blood pressure and may cause side effects.

Avoid becoming overheated or dehydrated during exercise, in hot weather, or by not drinking enough fluids.

What are the possible side effects of hydrochlorothiazide and losartan?

What are the possible side effects of hydrochlorothiazide and losartan?

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • a light-headed feeling, like you might pass out;
  • irregular heartbeats;
  • eye pain, vision problems;
  • kidney problems --little or no urination, rapid weight gain, swelling in your hands, feet, or ankles;
  • new or worsening symptoms of lupus --joint pain, and a skin rash on your cheeks or arms that worsens in sunlight; or
  • signs of an electrolyte imbalance --increased thirst or urination, confusion, vomiting, constipation, muscle pain, leg cramps, irregular heartbeats, numbness or tingling, severe weakness, loss of movement, feeling jittery or unsteady.

Common side effects may include:

  • dizziness;
  • back pain; or
  • cold symptoms such as stuffy nose, sneezing, sore throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect hydrochlorothiazide and losartan?

What other drugs will affect hydrochlorothiazide and losartan?

If you also take cholestyramine or colestipol, take your hydrochlorothiazide and losartan dose 4 hours before or 4 to 6 hours after you take the other medicine.

Tell your doctor about all your other medicines, especially:

  • a diuretic or "water pill";
  • other blood pressure medications;
  • lithium; or
  • NSAIDs (nonsteroidal anti-inflammatory drugs) --aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.

This list is not complete. Other drugs may affect hydrochlorothiazide and losartan, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Where can I get more information?

Where can I get more information?

Your pharmacist can provide more information about hydrochlorothiazide and losartan.

This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.

Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.

<cipublic-spinner variant="large"><span>Loading…</span></cipublic-spinner>

Page Footer

I want to...

Get an ID card File a claim View my claims and EOBs Check coverage under my plan See prescription drug list Find an in-network doctor, dentist, or facility Find a form Find 1095-B tax form information View the Cigna Glossary Contact Cigna

Audiences

Individuals and Families Medicare Employers Brokers Providers

Secure Member Sites

myCigna member portal Health Care Provider portal Cigna for Employers Client Resource Portal Cigna for Brokers

The Cigna Group Information

About The Cigna Group Company Profile Careers Newsroom Investors Suppliers The Cigna Group Third Party Administrators International Evernorth

 Cigna. All rights reserved.

Privacy Legal Product Disclosures Cigna Company Names Customer Rights Accessibility Non-Discrimination Notice Language Assistance [PDF] Report Fraud Sitemap Cookie Settings

Disclaimer

Individual and family medical and dental insurance plans are insured by Cigna Health and Life Insurance Company (CHLIC), Cigna HealthCare of Arizona, Inc., Cigna HealthCare of Illinois, Inc., Cigna HealthCare of Georgia, Inc., Cigna HealthCare of North Carolina, Inc., Cigna HealthCare of South Carolina, Inc., and Cigna HealthCare of Texas, Inc. Group health insurance and health benefit plans are insured or administered by CHLIC, Connecticut General Life Insurance Company (CGLIC), or their affiliates (see a listing of the legal entities that insure or administer group HMO, dental HMO, and other products or services in your state). Accidental Injury, Critical Illness, and Hospital Care plans or insurance policies are distributed exclusively by or through operating subsidiaries of Cigna Corporation, are administered by Cigna Health and Life Insurance Company, and are insured by either (i) Cigna Health and Life Insurance Company (Bloomfield, CT); (ii) Life Insurance Company of North America (“LINA”) (Philadelphia, PA); or (iii) New York Life Group Insurance Company of NY (“NYLGICNY”) (New York, NY), formerly known as Cigna Life Insurance Company of New York. The Cigna name, logo, and other Cigna marks are owned by Cigna Intellectual Property, Inc. LINA and NYLGICNY are not affiliates of Cigna.

All insurance policies and group benefit plans contain exclusions and limitations. For availability, costs and complete details of coverage, contact a licensed agent or Cigna sales representative. This website is not intended for residents of New Mexico.

Selecting these links will take you away from Cigna.com to another website, which may be a non-Cigna website. Cigna may not control the content or links of non-Cigna websites. Details