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Home Knowledge Center Wellness Library idarucizumab

idarucizumab

Pronunciation: EYE da roo KIZ ue mab

Brand: Praxbind

What is the most important information I should know about idarucizumab?

What is the most important information I should know about idarucizumab?

In an emergency, you may not be able to tell caregivers about your health conditions. Make sure any doctor caring for you afterward knows you received this medicine.

What is idarucizumab?

What is idarucizumab?

Idarucizumab is a drug that reverses the effects of another medicine called dabigatran (Pradaxa). Dabigatran is used to prevent blood clots and strokes in people with certain heart disorders. Because the medicine keeps the blood from clotting, people taking dabigatran can bleed more easily.

Idarucizumab is used during a medical emergency to treat severe or uncontrolled bleeding that has been caused by taking dabigatran.

Idarucizumab is also used when an emergency surgery or other invasive medical procedure is needed in a person who takes dabigatran.

Idarucizumab may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before receiving idarucizumab?

What should I discuss with my healthcare provider before receiving idarucizumab?

If possible before you receive idarucizumab, tell your doctor if you have hereditary fructose intolerance. Idarucizumab contains sorbitol (a sugar alcohol). Sorbitol can cause serious or life-threatening metabolic problems in people with hereditary fructose intolerance.

In an emergency, you may not be able to tell caregivers if you are pregnant or breast feeding. Make sure any doctor caring for your pregnancy or your baby knows you received this medicine.

How is idarucizumab given?

How is idarucizumab given?

Idarucizumab is given as an infusion into a vein. A healthcare provider will give you this injection.

After you receive idarucizumab, you may need follow-up blood tests to help your doctor determine how quickly your blood is clotting.

Once your condition is stable, you may need to restart dabigatran to prevent blood clots. Carefully follow your doctor's instructions about how soon to start taking your medicine(s) again.

What happens if I miss a dose?

What happens if I miss a dose?

Because you will receive idarucizumab in a clinical setting, you are not likely to miss a dose.

What happens if I overdose?

What happens if I overdose?

Since this medicine is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

What should I avoid after receiving idarucizumab?

What should I avoid after receiving idarucizumab?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What are the possible side effects of idarucizumab?

What are the possible side effects of idarucizumab?

Get emergency medical help if you have signs of an allergic reaction: hives, itching; difficult breathing; swelling of your face, lips, tongue, or throat.

When the effects of dabigatran are reversed, you will not be protected against blood clots. Because of this, you may be susceptible to the effects of your underlying disease. Until you start taking dabigatran again, watch for signs and symptoms of blood clots, such as:

  • sudden numbness or weakness (especially on one side of the body);
  • problems with vision or speech;
  • chest pain, wheezing, coughing up blood; or
  • pain, swelling, warmth, or redness in one or both legs.

After you receive idarucizumab, tell your caregivers right away if you have any bleeding that will not stop.

Common side effects may include:

  • confusion, headache;
  • fever; or
  • constipation.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect idarucizumab?

What other drugs will affect idarucizumab?

Other drugs may affect idarucizumab, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Where can I get more information?

Where can I get more information?

Your pharmacist can provide more information about idarucizumab.

This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.

Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.

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