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Home Knowledge Center Wellness Library idelalisib

idelalisib

Pronunciation: eye DEL a LIS ib

Brand: Zydelig

Zydelig

slide 1 of 1, Zydelig,

100 mg, oval, orange, imprinted with 100, GSI

Image of Zydelig
slide 1 of 1
What is the most important information I should know about idelalisib?

What is the most important information I should know about idelalisib?

Idelalisib can cause serious harm to your liver, lungs, or intestines. Some of these conditions may lead to fatal complications. Call your doctor right away if you have: upper stomach pain, easy bruising or bleeding, dark urine, yellowing of your skin or eyes, cough, wheezing, shortness of breath, fever, chills, worsening stomach pain, or vomiting.

You may have severe or life-threatening diarrhea while taking idelalisib. Tell your doctor at once if your daily bowel movements increase by 6 or more.

What is idelalisib?

What is idelalisib?

Idelalisib is used together with rituximab to treat chronic lymphocytic leukemia, and certain types of lymphoma.

Idelalisib is sometimes given after at least two other cancer treatments did not work or have stopped working.

Idelalisib was approved by the US Food and Drug Administration (FDA) on an "accelerated" basis to treat lymphoma. In clinical studies, some people responded to this medicine, but further studies are needed.

Idelalisib may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking idelalisib?

What should I discuss with my healthcare provider before taking idelalisib?

You may not be able to use idelalisib if you have ever had a serious skin reaction to any medicine.

Tell your doctor if you have ever had:

  • liver disease;
  • lung disease; or
  • a perforation (a hole or tear) in your intestines.

Idelalisib can harm an unborn baby if the mother or the father is using this medicine.

  • If you are a woman, do not use idelalisib if you are pregnant. You may need to have a negative pregnancy test before starting this treatment. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 1 month after your last dose.
  • If you are a man, use effective birth control if your sex partner is able to get pregnant. Keep using birth control for at least 3 months after your last dose.
  • Tell your doctor right away if a pregnancy occurs while either the mother or the father is using idelalisib.

Do not breastfeed while using this medicine, and for at least 1 month after your last dose.

Idelalisib is not approved for use by anyone younger than 18 years old.

How should I take idelalisib?

How should I take idelalisib?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

You may take idelalisib with or without food.

Swallow the tablet whole and do not crush, chew, or break it.

You may have severe or life-threatening diarrhea while taking idelalisib. Tell your doctor at once if your daily bowel movements increase by 6 or more.

You may need frequent medical tests to be sure this medicine is not causing harmful effects. Your cancer treatments may be delayed based on the results.

Do not stop using idelalisib without your doctor's advice.

Store this medicine in the original container at room temperature, away from moisture and heat.

What happens if I miss a dose?

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if you are more than 6 hours late for the dose. Do not take two doses at one time.

What happens if I overdose?

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking idelalisib?

What should I avoid while taking idelalisib?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What are the possible side effects of idelalisib?

What are the possible side effects of idelalisib?

Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include: skin rash, fever, swollen glands, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes.

Idelalisib can cause serious harm to your liver, lungs, or intestines. You may have severe or life-threatening diarrhea, or a perforation (a hole or tear) in your intestines. Some of these conditions may lead to fatal complications.

Call your doctor at once if you have:

  • severe diarrhea, increased number of stools per day;
  • easy bruising, unusual bleeding, purple or red spots under your skin;
  • intestinal problems --worsening stomach pain, fever, chills, vomiting;
  • liver problems --upper stomach pain, loss of appetite, dark urine, jaundice (yellowing of the skin or eyes);
  • lung problems --worsening cough, wheezing, cough with mucus, or shortness of breath;
  • low white blood cell counts --fever, mouth sores, skin sores, sore throat.

Your cancer treatments may be delayed or permanently discontinued if you have certain side effects.

Common side effects may include:

  • nausea, stomach pain, diarrhea;
  • fever, cough, lung problems;
  • low white blood cells;
  • abnormal liver function tests;
  • rash; or
  • feeling tired.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect idelalisib?

What other drugs will affect idelalisib?

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Other drugs may affect idelalisib, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Where can I get more information?

Where can I get more information?

Your doctor or pharmacist can provide more information about idelalisib.

This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.

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