Immune Globulin Intramuscular (Human)

IMPORTANT WARNING:

Immune globulin intramuscular (IMIG) may cause blood clots. Tell your doctor if you have or have ever had any conditions that affect blood clotting or history of a blood clot or if you have a catheter placed into a vein, high blood pressure, high cholesterol levels, diabetes, or if you are overweight or obese, an older adult, or are bedridden. Tell your doctor and pharmacist if you are taking or using any type of estrogen medication. If you experience any of the following symptoms, call your doctor or get emergency care immediately: pain and/or swelling of an arm or leg with warmthover the affected area, discoloration of an arm or leg, unexplained shortness ofbreath, acute chest pain or discomfort that worsens on deep breathing, unexplainedrapid pulse, numbness or weakness on one side of the body.

WHY is this medicine prescribed?

Immune globulin intramuscular (IMIG) is used to provide antibodies (protein produced by the body to fight infections) to help prevent disease after being exposed to hepatitis A (if exposed <2 weeks ago), or measles (if exposed <6 days ago and are not vaccinated against measles or had measles recently), varicella (chicken pox). IMIG is also used to provide antibodies after being exposed to rubella (German measles) to lessen the chance of harm to the fetus in pregnant women who will not consider having an abortion. IMIG is in a class of medications called immune globulins. It works by providing antibodies to fight infections.

Are there OTHER USES for this medicine?

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

HOW should this medicine be used?

IMIG comes as a solution to be given intramuscularly (into a muscle) into your upper arm or upper thigh by a doctor or nurse in a medical office or facility. It is usually given as a single dose, but additional doses may be given when used to prevent hepatitis A if traveling for more than 2 months to areas where the disease is common.

Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.

What SPECIAL PRECAUTIONS should I follow?

Before receiving IMIG,

• tell your doctor and pharmacist if you are allergic to immune globulin, any other medications, or any of the ingredients in IMIG. Ask your pharmacist for a list of the ingredients.

  tell your doctor if you are an IgA-deficient patient with antibodies to IgA and a history of allergic reactions.

• tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take.

• tell your doctor if you have or have ever had any of the conditions listed in the IMPORTANT WARNING section.

• tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while after or while receiving IMIG, call your doctor.

• do not have any vaccinations (live vaccines such as measles, mumps and rubella) without talking to your doctor.

What SPECIAL DIETARY instructions should I follow?

Unless your doctor tells you otherwise, continue your normal diet.

What SIDE EFFECTS can this medicine cause?

IMIG may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

• headache
• nausea
• pain, swelling, or redness at the place of injection

Some side effects can be serious. If you experience any of these symptoms or those listed in the IMPORTANT WARNING section, call your doctor immediately or get emergency medical care:

• fever, chills, tiredness, and other signs of infection

IMIG may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (https://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

What OTHER INFORMATION should I know?

Keep all appointments with your doctor.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.