mepivacaine

What is the most important information I should know about mepivacaine?

What is mepivacaine?

Mepivacaine is an anesthetic (numbing medicine) that blocks the nerve impulses that send pain signals to your brain.

Mepivacaine is used as a local (in only one area) anesthetic for an epidural or spinal block. It is also used as an anesthetic for dental procedures.

Mepivacaine may also be used for other purposes not listed in this medication guide.

What should I discuss with my health care provider before receiving mepivacaine?

To make sure mepivacaine is safe for you, tell your doctor if you have:

• liver or kidney disease;
• low or high blood pressure;
• heart disease or a history of stroke;
• heart rhythm disorder;
• coronary artery disease;
• epilepsy or other seizure disorder;
• a drug allergy; or
• if you regularly use any medicines (especially to treat migraine headache, depression, or mental illness).

How is mepivacaine given?

For an epidural or spinal block, mepivacaine is injected into an area of your lower back near your spine. You will receive this injection in a hospital or surgical setting.

For a dental procedure, mepivacaine is injected into the gum area inside your mouth. You will receive this injection in a dentist's office or oral surgery setting.

Your breathing, blood pressure, oxygen levels, and other vital signs may be watched closely while you are receiving mepivacaine.

What happens if I miss a dose?

Since mepivacaine is given as needed before a surgery or other medical procedure, you are not likely to be on a dosing schedule.

What happens if I overdose?

Overdose symptoms may include extreme drowsiness, seizure (convulsions), shallow breathing, or slow heart rate.

What should I avoid after receiving mepivacaine?

After your dental procedure, avoid eating, chewing gum, or drinking hot liquids until the feeling in your mouth has returned completely. Mepivacaine can cause numbness for a long period of time. Chewing while your mouth is numb could result in a bite injury to your tongue, lips, or inside of your cheek.

What are the possible side effects of mepivacaine?

• numbness and tingling in your mouth or lips, metallic taste in your mouth;
• ringing in your ears, blurred vision, slurred speech, headache;
• confusion, depression, severe drowsiness, feeling like you might pass out;
• slow heart rate, weak pulse, weak or shallow breathing;
• fever, neck stiffness, increased sensitivity to light;
• tremors or muscle twitching, feeling anxious or restless;
• ongoing numbness, weakness, or loss of movement in your legs or feet;
• loss of bladder or bowel control;
• loss of feeling in your lower stomach, groin, or genitals;
• painful or difficult urination; or
• fast heart rate, rapid breathing, feeling hot.

Common side effects may include:

• anxiety, feeling restless or excited;
• depression, dizziness;
• tremors; or
• blurred vision, ringing in your ears.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect mepivacaine?

Other drugs may interact with mepivacaine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Where can I get more information?

Your doctor or pharmacist can provide more information about mepivacaine.