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Home Knowledge Center Wellness Library mitotane

mitotane

Pronunciation: MYE toe tane

Brand: Lysodren

Lysodren

slide 1 of 1, Lysodren,

500 mg, round, white, imprinted with BL L1

Image of Lysodren
slide 1 of 1
What is the most important information I should know about mitotane?

What is the most important information I should know about mitotane?

You may need to take steroid medicine, or stop taking mitotane for a short time if you have a serious injury or medical emergency. Your doctor will determine when you can start taking this medicine again. Do not change your doses or medication schedule without advice from your doctor.

You must remain under the care of a doctor while taking mitotane.

What is mitotane?

What is mitotane?

Mitotane is used to treat cancer of the adrenal gland (adrenal cortical carcinoma).

Mitotane may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking mitotane?

What should I discuss with my healthcare provider before taking mitotane?

Tell your doctor if you have ever had:

  • recent infection, surgery, or trauma;
  • liver disease; or
  • if you take a blood thinner (warfarin, Coumadin, Jantoven).

Do not use mitotane if you are pregnant. This medicine could harm the unborn baby or cause miscarriage or premature birth. Use effective birth control to prevent pregnancy while you are using mitotane.

Do not breastfeed while using this medicine.

Follow your doctor's instructions about how long to avoid pregnancy and breastfeeding after your treatment ends. Mitotane can stay in your bloodstream long after you stop using it.

How should I take mitotane?

How should I take mitotane?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

You may need frequent medical tests. Even if you have no symptoms, tests can help your doctor determine if this medicine is effective.

You may need to take steroid medicine, or stop taking mitotane for a short time if you have a serious injury or medical emergency. Your doctor will determine when you can start taking this medicine again. Do not change your doses or medication schedule without advice from your doctor.

You must remain under the care of a doctor while taking mitotane.

Store mitotane at room temperature away from moisture and heat.

Ask your pharmacist how to safely handle mitotane tablets. You may need to wear latex gloves when handling this medicine. Do not use a broken tablet.

What happens if I miss a dose?

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking mitotane?

What should I avoid while taking mitotane?

Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.

Avoid activities that may increase your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth.

What are the possible side effects of mitotane?

What are the possible side effects of mitotane?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • blurred or double vision;
  • confusion, problems with speech, balance, or walking;
  • a light-headed feeling, like you might pass out;
  • pelvic pain, vaginal bleeding;
  • easy bruising or bleeding (nosebleeds, bleeding gums); or
  • any bleeding that will not stop.

Common side effects may include:

  • nausea, vomiting, loss of appetite;
  • diarrhea;
  • depressed mood;
  • dizziness, spinning sensation; or
  • rash.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect mitotane?

What other drugs will affect mitotane?

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Other drugs may affect mitotane, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Where can I get more information?

Where can I get more information?

Your doctor or pharmacist can provide more information about mitotane.

This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.

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