Skip to main navigation Skip to main content Skip to footer For Medicare For Providers For Brokers For Employers Español For Individuals & Families: For Individuals & Families Medical Dental Other Supplemental Explore coverage through work How to Buy Health Insurance Types of Dental Insurance Open Enrollment vs. Special Enrollment See all topics Shop for Medicare plans Member Guide Find a Doctor Log in to myCigna
Home Knowledge Center Wellness Library mobocertinib

mobocertinib

Brand: Exkivity

What is the most important information I should know about mobocertinib?

What is the most important information I should know about mobocertinib?

Call your doctor at once if you have fast or pounding heartbeats, fluttering in your chest, shortness of breath, and sudden dizziness (like you might pass out).

What is mobocertinib?

What is mobocertinib?

Mobocertinib is used in adults to treat non-small cell lung cancer that has spread to other parts of the body (metastatic) and cannot be removed with surgery, and whose disease has worsened while on or after chemotherapy with platinum.

Mobocertinib is used if your cancer has a specific genetic marker (an abnormal "EGFR" gene). Your doctor will test you for this gene.

Mobocertinib may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking mobocertinib?

What should I discuss with my healthcare provider before taking mobocertinib?

Tell your doctor if you have:

  • heart problems, including long QT syndrome;
  • an electrolyte imbalance (such as low blood levels of sodium, potassium, calcium, or magnesium); or
  • lung or breathing problems other than lung cancer.

You may need to have a negative pregnancy test before starting this treatment.

Both men and women using this medicine should use effective birth control to prevent pregnancy. Mobocertinib can harm an unborn baby if the mother or father is using this medicine.

Keep using birth control for at least 1 month for women and at least 1 week for men after your last dose. Tell your doctor right away if a pregnancy occurs.

Mobocertinib can make birth control pills less effective. Ask your doctor about other birth control options such as an injection, implant, skin patch, vaginal ring, condom, diaphragm, cervical cap, or contraceptive sponge.

Do not breastfeed while using this medicine, and for at least 1 week after your last dose.

Mobocertinib may affect fertility in men or women. Pregnancy could be harder to achieve while either parent is using this medicine.

How should I take mobocertinib?

How should I take mobocertinib?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

You may take mobocertinib with or without food.

Swallow the capsule whole and do not crush, chew, break, or open it.

You should not stop using mobocertinib without your doctor's advice.

Your cancer treatments may be delayed or permanently discontinued if you have certain side effects.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

What happens if I miss a dose?

Use the medicine as soon as you can, but skip the missed dose if you are more than 6 hours late for the dose. Do not use two doses at one time.

If you vomit shortly after taking mobocertinib, do not take another dose. Take your next dose as scheduled.

What happens if I overdose?

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking mobocertinib?

What should I avoid while taking mobocertinib?

Grapefruit may interact with mobocertinib and cause side effects. Avoid consuming grapefruit products.

What are the possible side effects of mobocertinib?

What are the possible side effects of mobocertinib?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • new or worsening breathing problems or shortness of breath, cough, or fever;
  • fast or pounding heartbeats, fluttering in your chest, swelling in your ankles or feet, chest pain, and sudden dizziness (like you might pass out); or
  • diarrhea.

Common side effects may include:

  • diarrhea, vomiting, nausea, decreased appetite;
  • rash, dry skin, skin infection around nails;
  • tiredness;
  • mouth sores; or
  • muscle or joint pain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect mobocertinib?

What other drugs will affect mobocertinib?

Sometimes it is not safe to use certain medicines at the same time. Some drugs can affect your blood levels of other drugs you use, which may increase side effects or make the medicines less effective.

Tell your doctor about all your other medicines, especially:

  • heart medication.

This list is not complete. Other drugs may affect mobocertinib, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Where can I get more information?

Where can I get more information?

Your doctor or pharmacist can provide more information about mobocertinib.

This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.

Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.

<cipublic-spinner variant="large"><span>Loading…</span></cipublic-spinner>

Page Footer

I want to...

Get an ID card File a claim View my claims and EOBs Check coverage under my plan See prescription drug list Find an in-network doctor, dentist, or facility Find a form Find 1095-B tax form information View the Cigna Glossary Contact Cigna

Audiences

Individuals and Families Medicare Employers Brokers Providers

Secure Member Sites

myCigna member portal Health Care Provider portal Cigna for Employers Client Resource Portal Cigna for Brokers

The Cigna Group Information

About The Cigna Group Company Profile Careers Newsroom Investors Suppliers The Cigna Group Third Party Administrators International Evernorth

 Cigna. All rights reserved.

Privacy Legal Product Disclosures Cigna Company Names Customer Rights Accessibility Non-Discrimination Notice Language Assistance [PDF] Report Fraud Sitemap Cookie Settings

Disclaimer

Individual and family medical and dental insurance plans are insured by Cigna Health and Life Insurance Company (CHLIC), Cigna HealthCare of Arizona, Inc., Cigna HealthCare of Illinois, Inc., Cigna HealthCare of Georgia, Inc., Cigna HealthCare of North Carolina, Inc., Cigna HealthCare of South Carolina, Inc., and Cigna HealthCare of Texas, Inc. Group health insurance and health benefit plans are insured or administered by CHLIC, Connecticut General Life Insurance Company (CGLIC), or their affiliates (see a listing of the legal entities that insure or administer group HMO, dental HMO, and other products or services in your state). Accidental Injury, Critical Illness, and Hospital Care plans or insurance policies are distributed exclusively by or through operating subsidiaries of Cigna Corporation, are administered by Cigna Health and Life Insurance Company, and are insured by either (i) Cigna Health and Life Insurance Company (Bloomfield, CT); (ii) Life Insurance Company of North America (“LINA”) (Philadelphia, PA); or (iii) New York Life Group Insurance Company of NY (“NYLGICNY”) (New York, NY), formerly known as Cigna Life Insurance Company of New York. The Cigna name, logo, and other Cigna marks are owned by Cigna Intellectual Property, Inc. LINA and NYLGICNY are not affiliates of Cigna.

All insurance policies and group benefit plans contain exclusions and limitations. For availability, costs and complete details of coverage, contact a licensed agent or Cigna sales representative. This website is not intended for residents of New Mexico.

Selecting these links will take you away from Cigna.com to another website, which may be a non-Cigna website. Cigna may not control the content or links of non-Cigna websites. Details