moxetumomab pasudotox

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moxetumomab pasudotox

Pronunciation: MOX e TOOM oh mab pa SOO doe tox

Brand: Lumoxiti

What is the most important information I should know about moxetumomab pasudotox?

Moxetumomab pasudotox can damage your kidneys, especially if you already have kidney disease or if you are 65 years of age or older. Get emergency medical help if you have: unusual bruising or bleeding, fever, confusion, tiredness or irritability, stomach pain, vomiting, dark urine, fast heartbeats, and little or no urination.

What is moxetumomab pasudotox?

Moxetumomab pasudotox is used to treat adults with hairy cell leukemia.

Moxetumomab pasudotox is given after at least two other cancer treatments did not work or have stopped working.

Moxetumomab pasudotox may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before receiving moxetumomab pasudotox?

Tell your doctor if you have ever had:

kidney disease; or
a condition that affects your blood and blood vessels (such as hemolytic uremic syndrome or severe thrombotic microangiopathy).

You may need to have a negative pregnancy test before starting this treatment.

Do not use moxetumomab pasudotox if you are pregnant. It could harm the unborn baby. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 30 days after your last dose. Tell your doctor right away if you become pregnant.

You should not breastfeed while using moxetumomab pasudotox.

How is moxetumomab pasudotox given?

Moxetumomab pasudotox is given as an infusion into a vein. A healthcare provider will give you this injection.

This medicine must be given slowly, and the infusion can take about 30 minutes to complete.

You may be given other medications to help prevent serious side effects or an infusion reaction. Keep using these medicines for as long as your doctor has prescribed.

Moxetumomab pasudotox is given in a 28-day treatment cycle. You may need to use the medicine only during the first week of each cycle. You may receive up to 6 treatment cycles. Your doctor will determine how long to treat you with this medicine.

During the first 8 days of each treatment cycle, drink up to 12 full 8-ounce glasses of water, milk, or juice every 24 hours.

What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your moxetumomab pasudotox injection.

What happens if I overdose?

Since this medicine is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

What should I avoid while receiving moxetumomab pasudotox?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What are the possible side effects of moxetumomab pasudotox?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Some side effects may occur during the injection. Tell your caregiver if you feel dizzy, nauseated, hot or cold, light-headed, or have a headache, muscle pain, cough, trouble breathing, or fast heartbeats.

Moxetumomab pasudotox can damage red blood cells, which may cause irreversible kidney failure. Get emergency medical help if you have: unusual bruising or bleeding, fever, confusion, tiredness or irritability, stomach pain, vomiting, dark urine, fast heartbeats, and little or no urination.

Call your doctor at once if you have:

low red blood cells (anemia) --pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands and feet;
signs of an electrolyte imbalance --muscle spasms or contractions, numbness or tingly feeling, nausea, fast or irregular heartbeats, seizure; or
capillary leak syndrome --dizziness, weakness, cough, trouble breathing, and sudden swelling or weight gain.

Serious side effects may be more likely in older adults.

Your cancer treatments may be delayed or permanently discontinued if you have certain side effects.

Common side effects may include:

swelling in your arms, legs, or face;
nausea, diarrhea, constipation;
headache, tiredness;
fever; or
anemia.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect moxetumomab pasudotox?

Other drugs may affect moxetumomab pasudotox, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Where can I get more information?

Your pharmacist can provide more information about moxetumomab pasudotox.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2023 Cerner Multum, Inc. Version: 2.01. Revision date: 8/5/2020.

Your use of the content provided in this service indicates that you have read, understood and agree to the End-User License Agreement, which can be accessed by End-User License Agreement, which can be accessed by clicking on this link.

This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.

Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.

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moxetumomab pasudotox

What is the most important information I should know about moxetumomab pasudotox?

What is moxetumomab pasudotox?

What should I discuss with my healthcare provider before receiving moxetumomab pasudotox?

How is moxetumomab pasudotox given?

What happens if I miss a dose?

What happens if I overdose?

What should I avoid while receiving moxetumomab pasudotox?

What are the possible side effects of moxetumomab pasudotox?

What other drugs will affect moxetumomab pasudotox?

Where can I get more information?

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