Skip to main navigation Skip to main content Skip to footer For Medicare For Providers For Brokers For Employers Español For Individuals & Families: For Individuals & Families Medical Dental Other Supplemental Explore coverage through work How to Buy Health Insurance Types of Dental Insurance Open Enrollment vs. Special Enrollment See all topics Shop for Medicare plans Member Guide Find a Doctor Log in to myCigna
Home Knowledge Center Wellness Library nafcillin (injection)

nafcillin (injection)

Pronunciation: naf SIL in

What is the most important information I should know about nafcillin?

What is the most important information I should know about nafcillin?

You should not use this medicine if you are allergic to any penicillin antibiotic.

What is nafcillin?

What is nafcillin?

Nafcillin is a penicillin antibiotic is used to treat many different types of infections, especially those caused by staphylococcus bacteria ("staph" infections).

Nafcillin may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before using nafcillin?

What should I discuss with my healthcare provider before using nafcillin?

You should not use this medicine if you are allergic to nafcillin or similar antibiotics, such as:

  • amoxicillin (Amoxil, Augmentin, and others);
  • ampicillin;
  • dicloxacillin;
  • oxacillin; or
  • penicillin.

Tell your doctor if you have ever had:

  • asthma;
  • allergies;
  • liver disease;
  • kidney disease; or
  • any type of allergy (especially to antibiotic medicine).

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

Nafcillin can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

How is nafcillin given?

How is nafcillin given?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Nafcillin is given as an infusion into a vein, or injected into a muscle. A healthcare provider will give your first dose and may teach you how to properly use the medication by yourself.

Infusion into a vein can take 30 to 60 minutes to complete.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you don't understand all instructions.

Nafcillin powder must be mixed with a liquid (diluent) before using it.

If you inject into a muscle, give the injection right away after mixing the powder and diluent.

If you inject into a vein, you may store the mixture at room temperature for up to 3 days, or in a refrigerator for up to 7 days. Do not use if the mixture has changed colors or has particles in it. Call your pharmacist for new medicine.

Store unmixed nafcillin powder at room temperature away from moisture and heat.

Your medicine may also be supplied as a premixed solution that has been frozen in a plastic container.

Store frozen nafcillin in a deep freezer, at -4 degrees Fahrenheit (-20 degrees Celsius).

Take the medicine out of the freezer and let it reach room temperature before injecting your dose. You may also thaw the medicine in a refrigerator. Do not use heat to thaw frozen nafcillin.

Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of infection that is resistant to medication. Nafcillin will not treat a viral infection such as the flu or a common cold.

Use a needle and syringe only once and then place them in a puncture-proof "sharps" container. Follow state or local laws about how to dispose of this container. Keep it out of the reach of children and pets.

What happens if I miss a dose?

What happens if I miss a dose?

Use the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not use two doses at one time.

What happens if I overdose?

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include agitation, confusion, hand tremors, hallucinations, seizure, or coma.

What should I avoid while using nafcillin?

What should I avoid while using nafcillin?

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor before using anti-diarrhea medicine.

What are the possible side effects of nafcillin?

What are the possible side effects of nafcillin?

Get emergency medical help if you have signs of an allergic reaction: hives, itching; fever, stomach pain, muscle or joint pain; difficulty breathing; swelling of your face, lips, tongue, or throat.

A delayed allergic reaction to nafcillin can occur as few as 2 days to as many as 4 weeks after you use the medication.

Call your doctor at once if you have:

  • burning, pain, or swelling around the IV needle when the medicine is injected;
  • severe stomach pain, diarrhea that is watery or bloody (even if it occurs months after your last dose);
  • little or no urination;
  • painful urination, blood or pus in your urine;
  • pain in your side or lower back;
  • pain, swelling, bruising, or skin changes where the medicine was injected;
  • skin rash, itching, joint pain, or not feeling well;
  • fever, chills, swollen glands, sore throat, cough, trouble breathing; or
  • blisters or ulcers in your mouth, red or swollen gums, trouble swallowing.

Common side effects may include:

  • nausea, vomiting, diarrhea;
  • skin rash;
  • black or "hairy" tongue; or
  • tenderness or irritation around the IV needle.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect nafcillin?

What other drugs will affect nafcillin?

Tell your doctor about all your other medicines, especially:

  • cyclosporine;
  • warfarin (Coumadin, Jantoven); or
  • a tetracycline antibiotic --doxycycline, minocycline, or tetracycline.

This list is not complete. Other drugs may affect nafcillin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Where can I get more information?

Where can I get more information?

Your pharmacist can provide more information about nafcillin.

This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.

Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.

<cipublic-spinner variant="large"><span>Loading…</span></cipublic-spinner>

Page Footer

I want to...

Get an ID card File a claim View my claims and EOBs Check coverage under my plan See prescription drug list Find an in-network doctor, dentist, or facility Find a form Find 1095-B tax form information View the Cigna Glossary Contact Cigna

Audiences

Individuals and Families Medicare Employers Brokers Providers

Secure Member Sites

myCigna member portal Health Care Provider portal Cigna for Employers Client Resource Portal Cigna for Brokers

Cigna Company Information

About Cigna Company Profile Careers Newsroom Investors Suppliers Third Party Administrators International Evernorth

 Cigna. All rights reserved.

Privacy Legal Product Disclosures Cigna Company Names Customer Rights Accessibility Non-Discrimination Notice [PDF] Language Assistance [PDF] Report Fraud Sitemap

Disclaimer

Individual and family medical and dental insurance plans are insured by Cigna Health and Life Insurance Company (CHLIC), Cigna HealthCare of Arizona, Inc., Cigna HealthCare of Illinois, Inc., and Cigna HealthCare of North Carolina, Inc. Group health insurance and health benefit plans are insured or administered by CHLIC, Connecticut General Life Insurance Company (CGLIC), or their affiliates (see a listing of the legal entities  that insure or administer group HMO, dental HMO, and other products or services in your state). Accidental Injury, Critical Illness, and Hospital Care plans or insurance policies are distributed exclusively by or through operating subsidiaries of Cigna Corporation, are administered by Cigna Health and Life Insurance Company, and are insured by either (i) Cigna Health and Life Insurance Company (Bloomfield, CT); (ii) Life Insurance Company of North America (“LINA”) (Philadelphia, PA); or (iii) New York Life Group Insurance Company of NY (“NYLGICNY”) (New York, NY), formerly known as Cigna Life Insurance Company of New York. The Cigna name, logo, and other Cigna marks are owned by Cigna Intellectual Property, Inc. LINA and NYLGICNY are not affiliates of Cigna.

All insurance policies and group benefit plans contain exclusions and limitations. For availability, costs and complete details of coverage, contact a licensed agent or Cigna sales representative. This website is not intended for residents of New Mexico.

Selecting these links will take you away from Cigna.com to another website, which may be a non-Cigna website. Cigna may not control the content or links of non-Cigna websites. Details