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Home Knowledge Center Wellness Library Natalizumab Injection (NATALIZUMAB - INJECTION)

Natalizumab Injection (NATALIZUMAB - INJECTION)

This medicine is used for the following purposes:

  • inflammatory bowel disease
  • multiple sclerosis

Brand Name(s): Tysabri

Generic Name: Natalizumab

Instructions

Instructions

This medicine will be given to you at the hospital or infusion center.

This medicine is given as an IV injection into a vein.

This medicine should be given over 60 minutes.

Always inspect the medicine before using.

The liquid should be clear and colorless.

Check the medicine before each use. If the liquid medicine has any particles in it, appears discolored, or if the vial appears damaged, do not use it.

Do not shake the medicine before using.

Keep medicine in refrigerator. Do not freeze. Protect from light.

This medicine should be given by a trained health care provider.

You must be monitored by a healthcare professional for at least 1 hour after each dose is given.

It is important that you keep taking each dose of this medicine on time even if you are feeling well.

If you miss a dose, contact your doctor for instructions.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

Talk to your doctor before taking other medicines, including aspirins and ibuprofen containing products. Speak to your doctor about which medicines are safe to use while you are on this medicine.

Keep all appointments for medical exams and tests while on this medicine.

Cautions

Cautions

During pregnancy, this medicine should be used only when clearly needed. Talk to your doctor about the risks and benefits.

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

Your doctor should check you for tuberculosis (TB) before you start this medicine and while you are using it. Tell your doctor if you are being treated for TB or any other infection.

This medicine is associated with a rare but very serious medical condition. Please speak with your doctor about symptoms you should look out for while on this medicine. Notify your doctor immediately if you develop those symptoms.

Some patients on this medicine have developed severe, life-threatening infections. Please speak with your doctor about the risks and benefits of using this medicine.

This medicine is associated with a rare, but serious problem of the liver. Speak to your doctor about the early signs of liver problems and the benefits and risks of using this medicine.

Call the doctor if there are any signs of confusion or unusual changes in behavior.

Family should check on the patient often. Call the doctor if patient becomes more depressed, has thoughts of suicide, or shows changes in behavior.

This medicine may reduce your body's ability to fight infections. Avoid contact with people with colds, flu or other infections. Contact your doctor if you develop fever, cough, sore throat, or chills.

Speak with your health care provider before receiving any vaccinations.

Do not breastfeed while on this medicine.

Some patients have serious side effects from this medicine. Ask your pharmacist to show you the information from the Food and Drug Administration (FDA) and discuss it with you.

Side Effects

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

  • swelling of the legs, feet, and hands
  • headaches
  • pain, redness, swelling near injection
  • pain in the joints
  • menstruation changes (missed or fewer periods)

Call your doctor or get medical help right away if you notice any of these more serious side effects:

  • severe abdominal or pelvic pain
  • loss of balance
  • bleeding or bruising
  • chest pain
  • difficulty concentrating
  • confusion
  • cough that does not go away
  • depression or feeling sad
  • dizziness
  • feeling of heat or flushing
  • fever or chills
  • severe or persistent headache
  • fast or irregular heart beats
  • signs of liver damage (such as yellowing of eye or skin, dark urine, or unusual tiredness)
  • mood changes
  • tight or rigid muscles
  • nausea
  • neck pain or stiffness
  • seizures
  • shortness of breath
  • sore throat
  • difficulty speaking
  • suicidal thoughts
  • unsteadiness while walking
  • upper respiratory infection
  • dark urine
  • blurring or changes of vision

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.

Please speak with your doctor, nurse, or pharmacist if you have any questions about this medicine.

This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.

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