Skip to main navigation Skip to main content Skip to footer For Medicare For Providers For Brokers For Employers Español For Individuals & Families: For Individuals & Families Medical Dental Other Supplemental Explore coverage through work How to Buy Health Insurance Types of Dental Insurance Open Enrollment vs. Special Enrollment See all topics Shop for Medicare plans Member Guide Find a Doctor Log in to myCigna
Home Knowledge Center Wellness Library opicapone

opicapone

Pronunciation: oh PIK a pone

Brand: Ongentys

Ongentys

slide 1 of 1, Ongentys,

25 mg, capsule, blue/pink, imprinted with OPC 25

Image of Ongentys
slide 1 of 1
What is the most important information I should know about opicapone?

What is the most important information I should know about opicapone?

Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.

What is opicapone?

What is opicapone?

Opicapone is used together with carbidopa and levodopa to treat symptoms of "off" episodes (stiffness, tremors, muscle spasms, poor muscle control) in people with Parkinson's disease.

Opicapone may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking opicapone?

What should I discuss with my healthcare provider before taking opicapone?

You should not use opicapone if you are allergic to it, or if you have a certain type of tumor that secretes hormones, such as:

  • pheochromocytoma (tumor of the adrenal gland); or
  • paraganglioma (tumor of the nerve cells).

Do not use opicapone if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, and tranylcypromine.

Tell your doctor if you have ever had:

  • a sleep disorder that causes daytime sleepiness;
  • narcolepsy or other conditions that cause sudden sleepiness;
  • uncontrolled muscle movements;
  • unusual and intense urges to act on impulse (such as gambling, binge-eating, or compulsive shopping);
  • mental illness, hallucinations, or psychosis;
  • liver disease; or
  • kidney disease.

Tell your doctor if you are pregnant or breastfeeding.

How should I take opicapone?

How should I take opicapone?

When you start or stop taking opicapone, your doctor may need to adjust the doses of any other medicines you take for Parkinson's disease.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Opicapone is usually taken at bedtime, on an empty stomach.

Do not eat for at least 1 hour before or 1 hour after taking this medicine.

Your blood pressure may need to be checked often.

Opicapone may cause you to fall asleep during normal daytime activities such as working, talking, eating, or driving. You may fall asleep suddenly, even after feeling alert. Tell your doctor if you have any problems with daytime sleepiness or drowsiness.

Do not change your doses or stop using any of your medicines without your doctor's advice. Tell your doctor if any of your medicines seem to stop working.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

What happens if I miss a dose?

Skip the missed dose and use your next dose the following night. Do not use two doses at one time.

What happens if I overdose?

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking opicapone?

What should I avoid while taking opicapone?

Avoid driving or hazardous activity until you know how this medicine will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.

What are the possible side effects of opicapone?

What are the possible side effects of opicapone?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • a light-headed feeling, like you might pass out;
  • confusion, hallucinations (hearing or seeing something that is not there);
  • aggression, agitation, unusual thoughts or behavior;
  • uncontrolled muscle movements in your face (chewing, lip smacking, frowning, tongue movement, blinking or eye movement); or
  • worsening tremors, stiffness, or muscle spasms.

You may have increased sexual urges, unusual urges to gamble, or other intense urges while taking this medicine. Talk with your doctor if this occurs.

Common side effects may include:

  • feeling light-headed;
  • uncontrolled muscle movement;
  • abnormal blood tests;
  • constipation; or
  • weight loss.

When you stop taking opicapone, watch for withdrawal symptoms such as: stiff muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, or feeling like you might pass out.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect opicapone?

What other drugs will affect opicapone?

Using opicapone with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.

Tell your doctor about all your other medicines, especially:

  • dobutamine;
  • dopamine;
  • epinephrine, norepinephrine; or
  • isoproterenol.

This list is not complete. Other drugs may affect opicapone, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Where can I get more information?

Where can I get more information?

Your pharmacist can provide more information about opicapone.

This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.

Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.

<cipublic-spinner variant="large"><span>Loading…</span></cipublic-spinner>

Page Footer

I want to...

Get an ID card File a claim View my claims and EOBs Check coverage under my plan See prescription drug list Find an in-network doctor, dentist, or facility Find a form Find 1095-B tax form information View the Cigna Glossary Contact Cigna

Audiences

Individuals and Families Medicare Employers Brokers Providers

Secure Member Sites

myCigna member portal Health Care Provider portal Cigna for Employers Client Resource Portal Cigna for Brokers

Cigna Company Information

About Cigna Company Profile Careers Newsroom Investors Suppliers Third Party Administrators International Evernorth

 Cigna. All rights reserved.

Privacy Legal Product Disclosures Cigna Company Names Customer Rights Accessibility Non-Discrimination Notice [PDF] Language Assistance [PDF] Report Fraud Sitemap

Disclaimer

Individual and family medical and dental insurance plans are insured by Cigna Health and Life Insurance Company (CHLIC), Cigna HealthCare of Arizona, Inc., Cigna HealthCare of Illinois, Inc., and Cigna HealthCare of North Carolina, Inc. Group health insurance and health benefit plans are insured or administered by CHLIC, Connecticut General Life Insurance Company (CGLIC), or their affiliates (see a listing of the legal entities  that insure or administer group HMO, dental HMO, and other products or services in your state). Accidental Injury, Critical Illness, and Hospital Care plans or insurance policies are distributed exclusively by or through operating subsidiaries of Cigna Corporation, are administered by Cigna Health and Life Insurance Company, and are insured by either (i) Cigna Health and Life Insurance Company (Bloomfield, CT); (ii) Life Insurance Company of North America (“LINA”) (Philadelphia, PA); or (iii) New York Life Group Insurance Company of NY (“NYLGICNY”) (New York, NY), formerly known as Cigna Life Insurance Company of New York. The Cigna name, logo, and other Cigna marks are owned by Cigna Intellectual Property, Inc. LINA and NYLGICNY are not affiliates of Cigna.

All insurance policies and group benefit plans contain exclusions and limitations. For availability, costs and complete details of coverage, contact a licensed agent or Cigna sales representative. This website is not intended for residents of New Mexico.

Selecting these links will take you away from Cigna.com to another website, which may be a non-Cigna website. Cigna may not control the content or links of non-Cigna websites. Details