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osilodrostat
osilodrostat
What is the most important information I should know about osilodrostat?
What is the most important information I should know about osilodrostat?
Osilodrostat can cause serious side effects, such as heartbeat problems or decreased adrenal gland hormones. Call your doctor at once if you have irregular heartbeats, stomach pain, vomiting, loss of appetite, tiredness, or feeling light-headed.
What is osilodrostat?
What is osilodrostat?
Osilodrostat is used in adults to treat Cushing's disease that cannot be treated with pituitary surgery.
Osilodrostat may also be used for purposes not listed in this medication guide.
What should I discuss with my healthcare provider before taking osilodrostat?
What should I discuss with my healthcare provider before taking osilodrostat?
Tell your doctor if you have ever had:
- a heart rhythm disorder;
- long QT syndrome (in you or a family member);
- congestive heart failure;
- high blood pressure;
- an electrolyte imbalance (such as low levels of potassium or magnesium in your blood);
- fluid retention; or
- liver disease.
Tell your doctor if you are pregnant or plan to become pregnant. It is not known whether osilodrostat will harm an unborn baby. However, having Cushing's disease during pregnancy may cause complications such as diabetes or eclampsia (dangerously high blood pressure that can lead to medical problems in both mother and baby). The benefit of treating Cushing's disease may outweigh any risks to the baby.
Do not breastfeed while using this medicine, and for at least 1 week after your last dose.
Osilodrostat is not approved for use by anyone younger than 18 years old.
How should I take osilodrostat?
How should I take osilodrostat?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.
You may take osilodrostat with or without food.
Your doctor will check your heart function using an electrocardiograph or ECG (sometimes called an EKG). Your next dose may be delayed based on the results of your ECG or other medical tests.
Do not change your dose or dosing schedule without your doctor's advice.
Store at room temperature away from moisture and heat.
What happens if I miss a dose?
What happens if I miss a dose?
Skip the missed dose and use your next dose at the regular time. Do not use two doses at one time.
What happens if I overdose?
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include nausea, vomiting, stomach pain, extreme tiredness, feeling light-headed, or fainting.
What should I avoid while taking osilodrostat?
What should I avoid while taking osilodrostat?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
What are the possible side effects of osilodrostat?
What are the possible side effects of osilodrostat?
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
- fast or pounding heartbeats, fluttering in your chest, shortness of breath, and sudden dizziness (like you might pass out);
- swelling in your feet or ankles, feeling short of breath;
- decreased adrenal gland hormones --nausea, vomiting, stomach pain, loss of appetite, feeling tired or light-headed, muscle or joint pain, skin discoloration, craving salty foods;
- increased adrenal gland hormones --hunger, weight gain, swelling, skin discoloration, slow wound healing, sweating, acne, increased body hair, tiredness, mood changes, muscle weakness, missed menstrual periods, sexual changes; or
- low potassium level --leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling.
Common side effects may include:
- nausea;
- feeling tired;
- headache; or
- swelling.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect osilodrostat?
What other drugs will affect osilodrostat?
Osilodrostat can cause a serious heart problem. Your risk may be higher if you also use certain other medicines for infections, asthma, heart problems, high blood pressure, depression, mental illness, cancer, malaria, or HIV.
Other drugs may affect osilodrostat, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.
Where can I get more information?
Where can I get more information?
Your pharmacist can provide more information about osilodrostat.
This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.
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