Skip to main navigation Skip to main content Skip to footer For Medicare For Providers For Brokers For Employers Español For Individuals & Families: For Individuals & Families Medical Dental Other Supplemental Explore coverage through work How to Buy Health Insurance Types of Dental Insurance Open Enrollment vs. Special Enrollment See all topics Shop for Medicare plans Member Guide Find a Doctor Log in to myCigna
Home Knowledge Center Wellness Library papaverine

papaverine

Pronunciation: pa PAV uh reen

What is the most important information I should know about papaverine?

What is the most important information I should know about papaverine?

You should not receive this medicine if you have a serious heart condition such as "AV block."

In an emergency situation it may not be possible to tell your caregivers about your health conditions. Make sure any doctor caring for you afterward knows you have received this medicine.

What is papaverine?

What is papaverine?

Papaverine is a vasodilator that relaxes smooth muscles in your blood vessels to help them dilate (widen). This lowers blood pressure and allows blood to flow more easily through your veins and arteries.

Papaverine is used to treat many conditions that cause spasm of smooth muscle. This includes chest pain, circulation problems, heart attack, or disorders of the stomach or gallbladder.

Papaverine is not for use in treating erectile dysfunction (impotence) and should not be injected into the penis. This practice has resulted in painful or prolonged erection that may require surgery to correct.

Papaverine may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before receiving papaverine?

What should I discuss with my healthcare provider before receiving papaverine?

You should not receive papaverine if you are allergic to it, or if you have:

  • a serious heart condition such as "AV block."

If possible before you receive papaverine, tell your doctor if you have:

  • heart disease;
  • high blood pressure;
  • glaucoma; or
  • liver disease.

It is not known whether papaverine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.

It is not known whether papaverine passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

In an emergency situation it may not be possible to tell your caregivers if you are pregnant or breast feeding. Make sure any doctor caring for your pregnancy or your baby knows you have received this medicine.

How is papaverine given?

How is papaverine given?

Papaverine is injected into a muscle, or into a vein through an IV. A healthcare provider will give you this injection.

When injected into a vein, papaverine must be given slowly (over 1 or 2 minutes) to prevent vein irritation or other side effects.

What happens if I miss a dose?

What happens if I miss a dose?

Because you will receive papaverine in a clinical setting, you are not likely to miss a dose.

What happens if I overdose?

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include weakness, drowsiness, dizziness, vomiting, double vision, sweating, warmth or redness, fast heartbeats, and uncontrolled eye movement.

What should I avoid after receiving papaverine?

What should I avoid after receiving papaverine?

This medicine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Drinking alcohol can increase certain side effects of papaverine.

What are the possible side effects of papaverine?

What are the possible side effects of papaverine?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • upper stomach pain, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
  • skin rash, bruising, severe tingling, numbness, pain, muscle weakness;
  • severe headache, blurred vision, fast heart rate, pounding in your neck or ears, anxiety, shortness of breath;
  • extreme drowsiness;
  • vision changes; or
  • pain, swelling, or redness where the medicine was injected.

Common side effects may include:

  • nausea, upset stomach, loss of appetite, constipation, diarrhea;
  • general ill feeling;
  • headache, drowsiness, dizziness or spinning sensation;
  • flushing (warmth, redness, or tingly feeling);
  • skin rash, increased sweating; or
  • tiredness, lack of energy.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect papaverine?

What other drugs will affect papaverine?

Taking this medicine with other drugs that make you sleepy can worsen this effect. Ask your doctor before taking papaverine with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures.

Other drugs may interact with papaverine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Where can I get more information?

Where can I get more information?

Your pharmacist can provide more information about papaverine.

This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.

Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.

<cipublic-spinner variant="large"><span>Loading…</span></cipublic-spinner>

Page Footer

I want to...

Get an ID card File a claim View my claims and EOBs Check coverage under my plan See prescription drug list Find an in-network doctor, dentist, or facility Find a form Find 1095-B tax form information View the Cigna Glossary Contact Cigna

Audiences

Individuals and Families Medicare Employers Brokers Providers

Secure Member Sites

myCigna member portal Health Care Provider portal Cigna for Employers Client Resource Portal Cigna for Brokers

The Cigna Group Information

About The Cigna Group Company Profile Careers Newsroom Investors Suppliers The Cigna Group Third Party Administrators International Evernorth

 Cigna. All rights reserved.

Privacy Legal Product Disclosures Cigna Company Names Customer Rights Accessibility Non-Discrimination Notice Language Assistance [PDF] Report Fraud Sitemap

Disclaimer

Individual and family medical and dental insurance plans are insured by Cigna Health and Life Insurance Company (CHLIC), Cigna HealthCare of Arizona, Inc., Cigna HealthCare of Illinois, Inc., Cigna HealthCare of Georgia, Inc., Cigna HealthCare of North Carolina, Inc., Cigna HealthCare of South Carolina, Inc., and Cigna HealthCare of Texas, Inc. Group health insurance and health benefit plans are insured or administered by CHLIC, Connecticut General Life Insurance Company (CGLIC), or their affiliates (see a listing of the legal entities that insure or administer group HMO, dental HMO, and other products or services in your state). Accidental Injury, Critical Illness, and Hospital Care plans or insurance policies are distributed exclusively by or through operating subsidiaries of Cigna Corporation, are administered by Cigna Health and Life Insurance Company, and are insured by either (i) Cigna Health and Life Insurance Company (Bloomfield, CT); (ii) Life Insurance Company of North America (“LINA”) (Philadelphia, PA); or (iii) New York Life Group Insurance Company of NY (“NYLGICNY”) (New York, NY), formerly known as Cigna Life Insurance Company of New York. The Cigna name, logo, and other Cigna marks are owned by Cigna Intellectual Property, Inc. LINA and NYLGICNY are not affiliates of Cigna.

All insurance policies and group benefit plans contain exclusions and limitations. For availability, costs and complete details of coverage, contact a licensed agent or Cigna sales representative. This website is not intended for residents of New Mexico.

Selecting these links will take you away from Cigna.com to another website, which may be a non-Cigna website. Cigna may not control the content or links of non-Cigna websites. Details