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patisiran

Pronunciation: PAT i SIR an

Brand: Onpattro

What is the most important information I should know about patisiran?

What is the most important information I should know about patisiran?

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

What is patisiran?

What is patisiran?

Patisiran is used to treat polyneuropathy (damage of multiple nerves throughout the body) in adults with hereditary transthyretin-mediated amyloidosis (hATTR).

Patisiran may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before using patisiran?

What should I discuss with my healthcare provider before using patisiran?

Before using patisiran tell your doctor about all your medical conditions or allergies.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

If you are pregnant, your name may be listed on a pregnancy registry to track the effects of patisiran on the baby.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

How is patisiran given?

How is patisiran given?

Patisiran is given as an infusion into a vein. A healthcare provider will give you this injection once every 3 weeks.

This medicine must be given slowly, and the infusion can take about 80 minutes to complete.

Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when patisiran is injected.

You may be given other medications to help prevent serious side effects or an infusion reaction.

Your doctor may have you take extra vitamin A while you are using patisiran. Take only the amount of vitamin A your doctor has prescribed, especially if you are pregnant. An overdose of vitamin A can cause vision problems or other serious side effects.

Call your doctor at once if you have vision problems (especially at night) while you are taking vitamin A.

Patisiran doses are based on weight. Your dose needs may change if you gain or lose weight.

You may need frequent medical tests. Even if you have no symptoms, tests can help your doctor determine if this medicine is effective. You may also need frequent eye exams.

What happens if I miss a dose?

What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your patisiran injection.

What happens if I overdose?

What happens if I overdose?

Since this medicine is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

What should I avoid while using patisiran?

What should I avoid while using patisiran?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What are the possible side effects of patisiran?

What are the possible side effects of patisiran?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Some side effects may occur during the injection. Tell your caregiver if you feel warm, dizzy, nauseated, light-headed, or have a headache, fast heartbeats, swelling in your face, stomach pain, chest pain, or trouble breathing.

Common side effects may include:

  • cold symptoms such as stuffy nose, sneezing, sore throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect patisiran?

What other drugs will affect patisiran?

Other drugs may affect patisiran, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Where can I get more information?

Where can I get more information?

Your pharmacist can provide more information about patisiran.

This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.

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