Skip to main navigation
Skip to main content
Skip to footer
For
Medicare
For
Providers
For
Brokers
For
Employers
Español
For Individuals & Families:
For Individuals & Families
Medical
Dental
Other Supplemental
Explore coverage through work
How to Buy Health Insurance
Types of Dental Insurance
Open Enrollment vs. Special Enrollment
See all topics
Shop for Medicare plans
Member Guide
Find a Doctor
Log in to myCigna
Home
Knowledge Center
Wellness Library
perindopril
perindopril
What is the most important information I should know about perindopril?
What is the most important information I should know about perindopril?
Do not use if you are pregnant. If you become pregnant, stop taking this medicine and tell your doctor right away.
You should not use perindopril if you have ever had angioedema. Do not take perindopril within 36 hours before or after taking medicine that contains sacubitril (such as Entresto).
If you have diabetes, do not use perindopril together with any medication that contains aliskiren (a blood pressure medicine).
What is perindopril?
What is perindopril?
Perindopril is an ACE inhibitors. ACE stands for angiotensin converting enzyme.
Perindopril is used to treat high blood pressure (hypertension) and to prevent heart attack in people with coronary artery disease.
Perindopril may also be used for purposes not listed in this medication guide.
What should I discuss with my healthcare provider before taking perindopril?
What should I discuss with my healthcare provider before taking perindopril?
You should not use this medicine if you are allergic to perindopril or if:
- you have hereditary angioedema;
- you recently took a heart medicine called sacubitril; or
- you are allergic to any other ACE inhibitor, such as benazepril, captopril, enalapril, fosinopril, lisinopril, moexipril, quinapril, ramipril, or trandolapril.
Do not take perindopril within 36 hours before or after taking medicine that contains sacubitril (such as Entresto).
If you have diabetes, do not use perindopril together with any medication that contains aliskiren (a blood pressure medicine).
You may also need to avoid taking perindopril with aliskiren if you have kidney disease.
Tell your doctor if you have ever had:
- kidney disease (or if you are on dialysis);
- liver disease;
- heart disease or congestive heart failure;
- diabetes; or
- a connective tissue disease such as Marfan syndrome, Sjogren's syndrome, lupus, scleroderma, or rheumatoid arthritis.
Do not use if you are pregnant, and tell your doctor right away if you become pregnant. Perindopril can cause injury or death to the unborn baby if you take the medicine during your second or third trimester.
It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.
How should I take perindopril?
How should I take perindopril?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.
Take each dose with a full glass of water. Drink plenty of liquids while you are taking perindopril.
You may take perindopril with or without food.
Your blood pressure will need to be checked often. Your kidney or liver function may also need to be checked.
Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking perindopril. This can lead to very low blood pressure, electrolyte disorders, or kidney failure.
If you need surgery, tell the surgeon ahead of time that you are using perindopril.
If you are being treated for high blood pressure, keep using this medication even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.
Store at room temperature away from moisture and heat.
What happens if I miss a dose?
What happens if I miss a dose?
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
What happens if I overdose?
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking perindopril?
What should I avoid while taking perindopril?
Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.
Do not use potassium supplements or salt substitutes, unless your doctor has told you to.
What are the possible side effects of perindopril?
What are the possible side effects of perindopril?
Get emergency medical help if you have signs of an allergic reaction: hives; severe stomach pain; difficulty breathing; swelling of your face, lips, tongue, or throat. You may be more likely to have an allergic reaction if you are African-American.
Call your doctor at once if you have:
- a light-headed feeling, like you might pass out;
- fever, chills, body aches, flu symptoms, sores in your mouth and throat;
- little or no urination;
- swelling, rapid weight gain;
- high potassium --nausea, slow or unusual heart rate, weakness, loss of movement;
- pale skin, easy bruising or bleeding; or
- jaundice (yellowing of the skin or eyes).
Common side effects may include:
- dizziness;
- back pain; or
- cough.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect perindopril?
What other drugs will affect perindopril?
Tell your doctor about all your other medicines, especially:
- lithium;
- a diuretic or "water pill";
- gold injections to treat arthritis; or
- NSAIDs (nonsteroidal anti-inflammatory drugs) --aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.
This list is not complete. Other drugs may affect perindopril, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
Where can I get more information?
Where can I get more information?
Your pharmacist can provide more information about perindopril.
This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.
Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.
<cipublic-spinner variant="large"><span>Loading…</span></cipublic-spinner>
