Skip to main navigation Skip to main content Skip to footer For Medicare For Providers For Brokers For Employers Español For Individuals & Families: For Individuals & Families Medical Dental Other Supplemental Explore coverage through work How to Buy Health Insurance Types of Dental Insurance Open Enrollment vs. Special Enrollment See all topics Shop for Medicare plans Member Guide Find a Doctor Log in to myCigna
Home Knowledge Center Wellness Library phendimetrazine

phendimetrazine

Pronunciation: fen di MEH tra zeen

Brand: Melfiat

Phendimetrazine Tartrate SR

slide 1 of 6, Phendimetrazine Tartrate SR,

105 mg, capsule, brown, imprinted with E5254

Image of Phendimetrazine Tartrate SR
slide 1 of 6

Bontril PDM

slide 2 of 6, Bontril PDM,

35 mg, round, green/yellow, imprinted with B 35, V

Image of Bontril PDM
slide 2 of 6

Bontril Slow Release

slide 3 of 6, Bontril Slow Release,

105 mg, green/yellow, imprinted with A, 047

Image of Bontril Slow Release
slide 3 of 6

Bontril Slow Release

slide 4 of 6, Bontril Slow Release,

105 mg, green/yellow, imprinted with C, 8647

Image of Bontril Slow Release
slide 4 of 6

Phendimetrazine Tartrate SR

slide 5 of 6, Phendimetrazine Tartrate SR,

105 mg, capsule, brown/clear, imprinted with E5254

Image of Phendimetrazine Tartrate SR
slide 5 of 6

Phendimetrazine Tartrate SR

slide 6 of 6, Phendimetrazine Tartrate SR,

105 mg, capsule, clear/brown, imprinted with E 5254

Image of Phendimetrazine Tartrate SR
slide 6 of 6
What is the most important information I should know about phendimetrazine?

What is the most important information I should know about phendimetrazine?

You should not use this medicine if you have glaucoma, overactive thyroid, severe heart problems, uncontrolled high blood pressure, advanced coronary artery disease, extreme agitation, or a history of drug abuse.

Do not use this medicine if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.

What is phendimetrazine?

What is phendimetrazine?

Phendimetrazine is similar to an amphetamine. Phendimetrazine stimulates the central nervous system (nerves and brain), which increases your heart rate and blood pressure and decreases your appetite.

Phendimetrazine is used together with diet and exercise to treat obesity.

Phendimetrazine may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking phendimetrazine?

What should I discuss with my healthcare provider before taking phendimetrazine?

You should not use phendimetrazine if you are allergic to it, or if you have:

  • severe heart problems;
  • advanced coronary artery disease (clogged arteries);
  • severe or uncontrolled high blood pressure;
  • overactive thyroid;
  • glaucoma;
  • extreme agitation or nervousness; or
  • a history of drug abuse.

Do not use phendimetrazine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

Weight loss during pregnancy can harm an unborn baby, even if you are overweight. Do not use phendimetrazine if you are pregnant. Tell your doctor right away if you become pregnant during treatment.

Tell your doctor if you have ever had:

  • heart disease or coronary artery disease;
  • high blood pressure;
  • diabetes (your diabetes medication dose may need to be adjusted); or
  • an allergy to food dye or aspirin.

Phendimetrazine is not approved for use by anyone younger than 12 years old.

It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.

How should I take phendimetrazine?

How should I take phendimetrazine?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Phendimetrazine is usually taken 1 hour before meals. Follow your doctor's dosing instructions very carefully.

Never use phendimetrazine in larger amounts, or for longer than prescribed. Taking more of this medication will not make it more effective and can cause serious, life-threatening side effects.

Phendimetrazine is for short-term use only. The effects of appetite suppression may wear off after a few weeks.

Phendimetrazine may be habit-forming. Misuse can cause addiction, overdose, or death. Selling or giving away this medicine is against the law.

Call your doctor at once if you think this medicine is not working as well, or if you have not lost at least 4 pounds within 4 weeks.

Do not stop using phendimetrazine suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using this medicine.

Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.

What happens if I miss a dose?

What happens if I miss a dose?

Use the medicine as soon as you can, but skip the missed dose if it is late in the day. Do not use two doses at one time.

What happens if I overdose?

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of phendimetrazine can be fatal.

Overdose symptoms may include confusion, panic, hallucinations, extreme restlessness, nausea, vomiting, diarrhea, stomach cramps, feeling tired or depressed, irregular heartbeats, weak pulse, seizure, or slow breathing (breathing may stop).

What should I avoid while taking phendimetrazine?

What should I avoid while taking phendimetrazine?

Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.

Drinking alcohol with this medicine can cause side effects.

What are the possible side effects of phendimetrazine?

What are the possible side effects of phendimetrazine?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • pounding heartbeats or fluttering in your chest;
  • tremors, severe agitation, feeling restless, trouble sleeping;
  • unusual changes in mood or behavior;
  • little or no urination; or
  • increased blood pressure --severe headache, blurred vision, pounding in your neck or ears, anxiety, nosebleed.

Common side effects may include:

  • flushing (warmth, redness, or tingly feeling);
  • increased sweating or urination;
  • dizziness, headache;
  • blurred vision;
  • dry mouth, nausea;
  • diarrhea, constipation, stomach pain; or
  • increased or decreased interest in sex.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect phendimetrazine?

What other drugs will affect phendimetrazine?

Other drugs may affect phendimetrazine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Where can I get more information?

Where can I get more information?

Your pharmacist can provide more information about phendimetrazine.

This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.

Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.

<cipublic-spinner variant="large"><span>Loading…</span></cipublic-spinner>

Page Footer

I want to...

Get an ID card File a claim View my claims and EOBs Check coverage under my plan See prescription drug list Find an in-network doctor, dentist, or facility Find a form Find 1095-B tax form information View the Cigna Glossary Contact Cigna

Audiences

Individuals and Families Medicare Employers Brokers Providers

Secure Member Sites

myCigna member portal Health Care Provider portal Cigna for Employers Client Resource Portal Cigna for Brokers

Cigna Company Information

About Cigna Company Profile Careers Newsroom Investors Suppliers Third Party Administrators International Evernorth

 Cigna. All rights reserved.

Privacy Legal Product Disclosures Cigna Company Names Customer Rights Accessibility Non-Discrimination Notice [PDF] Language Assistance [PDF] Report Fraud Sitemap

Disclaimer

Individual and family medical and dental insurance plans are insured by Cigna Health and Life Insurance Company (CHLIC), Cigna HealthCare of Arizona, Inc., Cigna HealthCare of Illinois, Inc., and Cigna HealthCare of North Carolina, Inc. Group health insurance and health benefit plans are insured or administered by CHLIC, Connecticut General Life Insurance Company (CGLIC), or their affiliates (see a listing of the legal entities  that insure or administer group HMO, dental HMO, and other products or services in your state). Accidental Injury, Critical Illness, and Hospital Care plans or insurance policies are distributed exclusively by or through operating subsidiaries of Cigna Corporation, are administered by Cigna Health and Life Insurance Company, and are insured by either (i) Cigna Health and Life Insurance Company (Bloomfield, CT); (ii) Life Insurance Company of North America (“LINA”) (Philadelphia, PA); or (iii) New York Life Group Insurance Company of NY (“NYLGICNY”) (New York, NY), formerly known as Cigna Life Insurance Company of New York. The Cigna name, logo, and other Cigna marks are owned by Cigna Intellectual Property, Inc. LINA and NYLGICNY are not affiliates of Cigna.

All insurance policies and group benefit plans contain exclusions and limitations. For availability, costs and complete details of coverage, contact a licensed agent or Cigna sales representative. This website is not intended for residents of New Mexico.

Selecting these links will take you away from Cigna.com to another website, which may be a non-Cigna website. Cigna may not control the content or links of non-Cigna websites. Details