Skip to main navigation Skip to main content Skip to footer For Medicare For Providers For Brokers For Employers Español For Individuals & Families: For Individuals & Families Medical Dental Other Supplemental Explore coverage through work How to Buy Health Insurance Types of Dental Insurance Open Enrollment vs. Special Enrollment See all topics Shop for Medicare plans Member Guide Find a Doctor Log in to myCigna
Home Knowledge Center Wellness Library remifentanil

remifentanil

Pronunciation: rem i FEN ta nil

Brand: Ultiva

What is the most important information I should know about remifentanil?

What is the most important information I should know about remifentanil?

MISUSE OF OPIOID MEDICINE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. `

What is remifentanil?

What is remifentanil?

Remifentanil is an opioid medication that is used to treat or prevent pain during and after surgery or other medical procedures.

Remifentanil may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before I receive remifentanil?

What should I discuss with my healthcare provider before I receive remifentanil?

You should not be treated with remifentanil if you are allergic to it.

Tell your doctor if you have ever had:

  • breathing problems, sleep apnea;
  • a head injury, brain tumor, or seizure;
  • problems with your gallbladder or pancreas;
  • alcoholism or drug addiction;
  • if you have recently used alcohol, sedatives, tranquilizers, or other opioid medications; or
  • if you have taken an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, or tranylcypromine.

Receiving remifentanil during late pregnancy may cause side effects in the newborn baby, including severe drowsiness and breathing problems. Your baby's breathing, blood pressure, oxygen levels, and other vital signs will be watched closely.

Ask a doctor before using opioid medicine if you are breastfeeding. Tell your doctor if you notice severe drowsiness or slow breathing in the nursing baby.

How is remifentanil given?

How is remifentanil given?

MISUSE OF OPIOID MEDICINE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH.

Remifentanil is injected into a vein by a healthcare provider.

Remifentanil is usually given through an infusion connected to pump that will release the correct dose of the medication to provide continuous pain relief during and after your surgery.

Your breathing, blood pressure, oxygen levels, kidney function, and other vital signs will be watched closely.

You may be given other pain medications to use after your remifentanil treatment is discontinued. Keep using these medicines for as long as your doctor has prescribed.

What happens if I miss a dose?

What happens if I miss a dose?

In a medical setting you are not likely to miss a dose.

What happens if I overdose?

What happens if I overdose?

A remifentanil overdose can be fatal. Overdose symptoms may include slow breathing and heart rate, severe drowsiness, muscle weakness, cold and clammy skin, pinpoint pupils, and fainting.

In a medical setting an overdose would be treated quickly.

What should I avoid after receiving remifentanil?

What should I avoid after receiving remifentanil?

Do not drink alcohol for at least 24 hours after your surgery. Dangerous side effects or death could occur.

Avoid driving or hazardous activity until you know how this medicine will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.

What are the possible side effects of remifentanil?

What are the possible side effects of remifentanil?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Opioid medicine can slow or stop your breathing, and death may occur. A person caring for you should seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, or if you are hard to wake up.

Your caregivers will watch for any side effects you have, such as:

  • shallow breathing, breathing that stops during sleep;
  • fast or slow heart rate;
  • stiff muscles;
  • low blood pressure (severe weakness, feeling light-headed); or
  • serotonin syndrome --agitation, hallucinations, fever, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, diarrhea.

Serious breathing problems may be more likely in older adults and in those who are debilitated or have wasting syndrome or chronic breathing disorders.

Common side effects may include:

  • slow breathing;
  • slow heart rate;
  • muscle stiffness; or
  • low blood pressure.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect remifentanil?

What other drugs will affect remifentanil?

Many other drugs can be dangerous when used with opioid medicine. Tell your doctor if you also use:

  • other opioid medicines;
  • a benzodiazepine sedative like Valium, Klonopin, or Xanax;
  • sleep medicine, muscle relaxers, or other drugs that make you drowsy; or
  • drugs that affect serotonin, such as antidepressants, stimulants, or medicine for migraines or Parkinson's disease.

This list is not complete. Many drugs may affect remifentanil, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here.

Where can I get more information?

Where can I get more information?

Your doctor or pharmacist can provide more information about remifentanil.

This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.

Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.

<cipublic-spinner variant="large"><span>Loading…</span></cipublic-spinner>

Page Footer

I want to...

Get an ID card File a claim View my claims and EOBs Check coverage under my plan See prescription drug list Find an in-network doctor, dentist, or facility Find a form Find 1095-B tax form information View the Cigna Glossary Contact Cigna

Audiences

Individuals and Families Medicare Employers Brokers Providers

Secure Member Sites

myCigna member portal Health Care Provider portal Cigna for Employers Client Resource Portal Cigna for Brokers

Cigna Company Information

About Cigna Company Profile Careers Newsroom Investors Suppliers Third Party Administrators International Evernorth

 Cigna. All rights reserved.

Privacy Legal Product Disclosures Cigna Company Names Customer Rights Accessibility Non-Discrimination Notice [PDF] Language Assistance [PDF] Report Fraud Sitemap

Disclaimer

Individual and family medical and dental insurance plans are insured by Cigna Health and Life Insurance Company (CHLIC), Cigna HealthCare of Arizona, Inc., Cigna HealthCare of Illinois, Inc., and Cigna HealthCare of North Carolina, Inc. Group health insurance and health benefit plans are insured or administered by CHLIC, Connecticut General Life Insurance Company (CGLIC), or their affiliates (see a listing of the legal entities  that insure or administer group HMO, dental HMO, and other products or services in your state). Accidental Injury, Critical Illness, and Hospital Care plans or insurance policies are distributed exclusively by or through operating subsidiaries of Cigna Corporation, are administered by Cigna Health and Life Insurance Company, and are insured by either (i) Cigna Health and Life Insurance Company (Bloomfield, CT); (ii) Life Insurance Company of North America (“LINA”) (Philadelphia, PA); or (iii) New York Life Group Insurance Company of NY (“NYLGICNY”) (New York, NY), formerly known as Cigna Life Insurance Company of New York. The Cigna name, logo, and other Cigna marks are owned by Cigna Intellectual Property, Inc. LINA and NYLGICNY are not affiliates of Cigna.

All insurance policies and group benefit plans contain exclusions and limitations. For availability, costs and complete details of coverage, contact a licensed agent or Cigna sales representative. This website is not intended for residents of New Mexico.

Selecting these links will take you away from Cigna.com to another website, which may be a non-Cigna website. Cigna may not control the content or links of non-Cigna websites. Details