Skip to main navigation Skip to main content Skip to footer For Medicare For Providers For Brokers For Employers Español For Individuals & Families: For Individuals & Families Medical Dental Other Supplemental Explore coverage through work How to Buy Health Insurance Types of Dental Insurance Open Enrollment vs. Special Enrollment See all topics Shop for Medicare plans Member Guide Find a Doctor Log in to myCigna
Home Knowledge Center Wellness Library rifabutin

rifabutin

Pronunciation: RIF a BUE tin

Brand: Mycobutin

Mycobutin

slide 1 of 3, Mycobutin,

150 mg, capsule, red, imprinted with MYCOBUTIN, Pharmacis&Upjohn

Image of Mycobutin
slide 1 of 3

Rifabutin

slide 2 of 3, Rifabutin,

150 mg, capsule, red, imprinted with MYCOBUTIN, Pharmacia & Upjohn

Image of Rifabutin
slide 2 of 3

Rifabutin

slide 3 of 3, Rifabutin,

150 mg, capsule, red, imprinted with LU, R01

Image of Rifabutin
slide 3 of 3
What is the most important information I should know about rifabutin?

What is the most important information I should know about rifabutin?

You should not use rifabutin if you have active tuberculosis, or if you are also taking delavirdine or voriconazole.

What is rifabutin?

What is rifabutin?

Rifabutin is an antibiotic that fights bacteria.

Rifabutin is used to prevent mycobacterium avium complex (MAC) in people with HIV (human immunodeficiency virus) infection.

Rifabutin is also used with other medicines to treat tuberculosis in people with HIV.

Rifabutin may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking rifabutin?

What should I discuss with my healthcare provider before taking rifabutin?

You should not use rifabutin if you are allergic to it, or if you have:

  • active tuberculosis; or
  • if you are allergic to rifapentine or rifampin.

Tell your doctor if you have ever had tuberculosis, if anyone in your household has tuberculosis, or if you have recently traveled to an area where tuberculosis is common.

Some medicines can interact with rifabutin and should not be used at the same time. Your doctor may need to change your treatment plan if you take:

  • delavirdine; or
  • voriconazole.

To make sure rifabutin is safe for you, tell your doctor if you have:

  • kidney disease;
  • liver disease; or
  • a history of an eye condition called uveitis.

This medicine is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

Rifabutin can make birth control pills less effective. Ask your doctor about using non hormonal birth control (condom, diaphragm with spermicide) to prevent pregnancy.

It is not known whether rifabutin passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.

How should I take rifabutin?

How should I take rifabutin?

Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Rifabutin may be taken with food if it upsets your stomach.

If you develop signs of tuberculosis while taking rifabutin, you should be treated with tuberculosis medications right away. Taking only rifabutin while you have active tuberculosis could make the infection resistant to antibiotics. Call your doctor if you have any signs of tuberculosis: fever, cough, night sweats, loss of appetite, weight loss, and feeling constantly tired.

While using rifabutin, you may need frequent blood tests and chest x-rays.

Use this medicine for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. Rifabutin will not treat a viral infection such as the flu or a common cold.

Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.

What happens if I miss a dose?

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking rifabutin?

What should I avoid while taking rifabutin?

Avoid wearing dentures or contact lenses. Rifabutin may cause certain body fluids to turn red, orange, or brown. This includes tears and saliva. Although this is a harmless side effect, discolored tears or saliva could permanently stain your contact lenses or dentures.

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor. Do not use anti-diarrhea medicine unless your doctor tells you to.

What are the possible side effects of rifabutin?

What are the possible side effects of rifabutin?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • severe stomach pain, diarrhea that is watery or bloody;
  • severe eye redness, small white or yellow patches on the surface of your eye; or
  • low white blood cell counts --fever, swollen gums, painful mouth sores, pain when swallowing, skin sores, cold or flu symptoms, cough, trouble breathing;

Common side effects may include:

  • red, orange, or brown discoloration of your skin, tears, sweat, saliva, urine, or stools;
  • gas, burping, upset stomach;
  • rash; or
  • muscle pain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect rifabutin?

What other drugs will affect rifabutin?

Many drugs can interact with rifabutin. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any you start or stop using, especially:

  • certain antibiotics --clarithromycin, erythromycin, telithromycin;
  • antifungal medicine --fluconazole, itraconazole, posaconazole;
  • hepatitis C medicine --boceprevir, simeprevir, telaprevir; or
  • HIV or AIDS medicine --fosamprenavir, indinavir, lopinavir, nelfinavir, ritonavir, saquinavir, zidovudine.

This list is not complete and many other drugs can interact with rifabutin. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.

Where can I get more information?

Where can I get more information?

Your pharmacist can provide more information about rifabutin.

This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.

Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.

<cipublic-spinner variant="large"><span>Loading…</span></cipublic-spinner>

Page Footer

I want to...

Get an ID card File a claim View my claims and EOBs Check coverage under my plan See prescription drug list Find an in-network doctor, dentist, or facility Find a form Find 1095-B tax form information View the Cigna Glossary Contact Cigna

Audiences

Individuals and Families Medicare Employers Brokers Providers

Secure Member Sites

myCigna member portal Health Care Provider portal Cigna for Employers Client Resource Portal Cigna for Brokers

Cigna Company Information

About Cigna Company Profile Careers Newsroom Investors Suppliers Third Party Administrators International Evernorth

 Cigna. All rights reserved.

Privacy Legal Product Disclosures Cigna Company Names Customer Rights Accessibility Non-Discrimination Notice [PDF] Language Assistance [PDF] Report Fraud Sitemap

Disclaimer

Individual and family medical and dental insurance plans are insured by Cigna Health and Life Insurance Company (CHLIC), Cigna HealthCare of Arizona, Inc., Cigna HealthCare of Illinois, Inc., and Cigna HealthCare of North Carolina, Inc. Group health insurance and health benefit plans are insured or administered by CHLIC, Connecticut General Life Insurance Company (CGLIC), or their affiliates (see a listing of the legal entities  that insure or administer group HMO, dental HMO, and other products or services in your state). Accidental Injury, Critical Illness, and Hospital Care plans or insurance policies are distributed exclusively by or through operating subsidiaries of Cigna Corporation, are administered by Cigna Health and Life Insurance Company, and are insured by either (i) Cigna Health and Life Insurance Company (Bloomfield, CT); (ii) Life Insurance Company of North America (“LINA”) (Philadelphia, PA); or (iii) New York Life Group Insurance Company of NY (“NYLGICNY”) (New York, NY), formerly known as Cigna Life Insurance Company of New York. The Cigna name, logo, and other Cigna marks are owned by Cigna Intellectual Property, Inc. LINA and NYLGICNY are not affiliates of Cigna.

All insurance policies and group benefit plans contain exclusions and limitations. For availability, costs and complete details of coverage, contact a licensed agent or Cigna sales representative. This website is not intended for residents of New Mexico.

Selecting these links will take you away from Cigna.com to another website, which may be a non-Cigna website. Cigna may not control the content or links of non-Cigna websites. Details