Skip to main navigation

Skip to footer

For Medicare For Providers For Brokers For Employers

Español

For Individuals & Families:

For Individuals & Families

Shop for Plans

Medical

Dental

Other Supplemental

Explore coverage through work

How to Buy Health Insurance

Types of Dental Insurance

Open Enrollment vs. Special Enrollment

See all topics

Shop for Medicare plans

Member Guide

Find a Doctor

Home

Knowledge Center

Wellness Library

Selexipag Injection

(se lex' i pag)

WHY is this medicine prescribed?

Selexipag injection is used in adults who are taking selexipag tablets to treat pulmonary arterial hypertension (PAH, high blood pressure in the vessels that carry blood to the lungs) but are temporarily unable to take medications by mouth. Selexipag injection is in a class of medications called selective nonprostanoid IP prostacyclin receptor agonists. It works by relaxing the blood vessels in the lungs to allow blood to flow easily.

Are there OTHER USES for this medicine?

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

HOW should this medicine be used?

Selexipag injection comes as a solution (liquid) to be injected intravenously (into a vein). It is usually injected slowly over 80 minutes by a doctor or a nurse. It is usually given twice a day for as long as you are unable to take selexipag tablets by mouth.

Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.

What SPECIAL PRECAUTIONS should I follow?

Before taking selexipag injection,

tell your doctor and pharmacist if you are allergic to selexipag, any other medications, or any of the ingredients in selexipag injection. Ask your pharmacist for a list of the ingredients.
tell your doctor if you are taking gemfibrozil (Lopid). Your doctor may tell you not to take selexipag injection if you are taking this medication.
tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: clopidogrel (Plavix), deferasirox (Exjade, Ferriprox, Jadenu), rifampin (Rifadin, Rimactane), and teriflunomide (Aubagio). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Many other medications may also interact with selexipag injection, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.
tell your doctor if you have or have ever had pulmonary veno-occlusive disease (PVOD; blockage of veins in the lungs), thyroid problems, or liver disease.
tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while receiving selexipag injection, call your doctor.

What SPECIAL DIETARY instructions should I follow?

Unless your doctor tells you otherwise, continue your normal diet.

What SIDE EFFECTS can this medicine cause?

Selexipag injection may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

redness, pain, tenderness, swelling, discoloration, itching, or bruising of the skin where selexipag was injected
headache
pain in jaw, joints, muscles, arms, or legs
decreased appetite
nausea
diarrhea
vomiting
flushing
rash

Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:

shortness of breath
rapid breathing
dizziness
weakness

Selexipag injection may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

What OTHER INFORMATION should I know?

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Brand Name(s): Uptravi^®

This report on medications is for your information only, and is not considered individual patient advice. Because of the changing nature of drug information, please consult your physician or pharmacist about specific clinical use.

The American Society of Health-System Pharmacists, Inc. represents that the information provided hereunder was formulated with a reasonable standard of care, and in conformity with professional standards in the field. The American Society of Health-System Pharmacists, Inc. makes no representations or warranties, express or implied, including, but not limited to, any implied warranty of merchantability and/or fitness for a particular purpose, with respect to such information and specifically disclaims all such warranties. Users are advised that decisions regarding drug therapy are complex medical decisions requiring the independent, informed decision of an appropriate health care professional, and the information is provided for informational purposes only. The entire monograph for a drug should be reviewed for a thorough understanding of the drug's actions, uses and side effects. The American Society of Health-System Pharmacists, Inc. does not endorse or recommend the use of any drug. The information is not a substitute for medical care.

AHFS^® Patient Medication Information™. © Copyright, 2024. The American Society of Health-System Pharmacists^®, 4500 East-West Highway, Suite 900, Bethesda, Maryland. All Rights Reserved. Duplication for commercial use must be authorized by ASHP.

Selected Revisions: January 15, 2022.

This information does not replace the advice of a doctor. Ignite Healthwise, LLC, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.

Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Ignite Healthwise, LLC.

<cipublic-spinner variant="large"><span>Loading…</span></cipublic-spinner>

Page Footer

I want to...

Get an ID card

File a claim

View my claims and EOBs

Check coverage under my plan

See prescription drug list

Find an in-network doctor, dentist, or facility

Find a form

Find 1095-B tax form information

View the Cigna Glossary

Contact Cigna

Audiences

Individuals and Families

Medicare

Employers

Brokers

Providers

Secure Member Sites

myCigna member portal

Health Care Provider portal

Cigna for Employers

Client Resource Portal

Cigna for Brokers

The Cigna Group Information

About Cigna Healthcare

Company Profile

Careers

Newsroom

Investors

Suppliers

The Cigna Group

Third Party Administrators

International

Evernorth

Privacy

Legal

Product Disclosures

Cigna Company Names

Customer Rights

Accessibility

Non-Discrimination Notice

Language Assistance [PDF]

Report Fraud

Sitemap

Cookie Settings

Disclaimer

Individual and family medical and dental insurance plans are insured by Cigna Health and Life Insurance Company (CHLIC), Cigna HealthCare of Arizona, Inc., Cigna HealthCare of Illinois, Inc., Cigna HealthCare of Georgia, Inc., Cigna HealthCare of North Carolina, Inc., Cigna HealthCare of South Carolina, Inc., and Cigna HealthCare of Texas, Inc. Group health insurance and health benefit plans are insured or administered by CHLIC, Connecticut General Life Insurance Company (CGLIC), or their affiliates (see a listing of the legal entities that insure or administer group HMO, dental HMO, and other products or services in your state). Accidental Injury, Critical Illness, and Hospital Care plans or insurance policies are distributed exclusively by or through operating subsidiaries of Cigna Corporation, are administered by Cigna Health and Life Insurance Company, and are insured by either (i) Cigna Health and Life Insurance Company (Bloomfield, CT); (ii) Life Insurance Company of North America (“LINA”) (Philadelphia, PA); or (iii) New York Life Group Insurance Company of NY (“NYLGICNY”) (New York, NY), formerly known as Cigna Life Insurance Company of New York. The Cigna name, logo, and other Cigna marks are owned by Cigna Intellectual Property, Inc. LINA and NYLGICNY are not affiliates of Cigna.

All insurance policies and group benefit plans contain exclusions and limitations. For availability, costs and complete details of coverage, contact a licensed agent or Cigna sales representative. This website is not intended for residents of New Mexico.

Selecting these links will take you away from Cigna.com to another website, which may be a non-Cigna website. Cigna may not control the content or links of non-Cigna websites. Details