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Home Knowledge Center Wellness Library silver sulfadiazine topical

silver sulfadiazine topical

Pronunciation: SIL ver SUL fa DYE a zeen TOP ik al

Brand: Silvadene, SSD, Thermazene

What is the most important information I should know about silver sulfadiazine topical?

What is the most important information I should know about silver sulfadiazine topical?

Silver sulfadiazine topical may cause serious medical problems in a newborn if you use this medicine during late pregnancy (close to your delivery date). This medicine should also not be used on premature babies or any child younger than 2 months old.

What is silver sulfadiazine topical?

What is silver sulfadiazine topical?

Silver sulfadiazine is an antibiotic. It fights bacteria and yeast on the skin.

Silver sulfadiazine topical (for the skin) is used to treat or prevent serious infection on areas of skin with second- or third-degree burns.

Silver sulfadiazine topical may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before using silver sulfadiazine topical?

What should I discuss with my healthcare provider before using silver sulfadiazine topical?

You should not use this medicine if you are allergic to silver sulfadiazine.

Silver sulfadiazine topical may cause serious medical problems in a newborn if you use this medicine during late pregnancy (close to your delivery date). This medicine should also not be used on premature babies or any child younger than 2 months old.

To make sure silver sulfadiazine topical is safe for you, tell your doctor if you have:

  • liver disease;
  • kidney disease;
  • a genetic enzyme deficiency called glucose-6-phosphate dehydrogenase (G6PD) deficiency; or
  • an allergy to sulfa drugs.

FDA pregnancy category B. Silver sulfadiazine topical is not expected to harm an unborn baby. However, this medicine can cause serious medical problems in a newborn and should not be used during late pregnancy.

It is not known whether silver sulfadiazine topical passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.

How should I use silver sulfadiazine topical?

How should I use silver sulfadiazine topical?

Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Wash your hands before and after applying silver sulfadiazine cream.

The person applying silver sulfadiazine to burn wounds should wear sterile disposable gloves. Take care to keep the treatment area as clean as possible to prevent further infection.

Clean the area to be treated as directed by your doctor. Apply enough silver sulfadiazine to cover the affected area evenly. This medicine should be applied in a layer about one 16th (1/16) of an inch thick, or 1.6 millimeters.

If needed, apply more cream to replace any medicine that has come off on bandages, clothing, or bed linens. Reapply the cream after bathing or water therapy.

Silver sulfadiazine cream is usually applied 1 or 2 times daily. Burn wounds must be kept covered with this medicine at all times. Treated skin areas can be left uncovered, or you may use a gauze bandage if directed by your doctor.

While using silver sulfadiazine topical, you may need frequent blood tests. Your kidney function may also need to be tested.

Use this medicine for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

What happens if I miss a dose?

Apply the missed dose as soon as you remember. Your burn wounds should be kept covered with silver sulfadiazine cream at all times.

What happens if I overdose?

What happens if I overdose?

An overdose of silver sulfadiazine topical is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.

What should I avoid while using silver sulfadiazine topical?

What should I avoid while using silver sulfadiazine topical?

Do not take by mouth. Silver sulfadiazine topical is for use only on the skin. If this medicine gets in your eyes, nose, or mouth, rinse with water.

What are the possible side effects of silver sulfadiazine topical?

What are the possible side effects of silver sulfadiazine topical?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Although the risk of serious side effects is low when silver sulfadiazine is applied to the skin, side effects can occur if the medicine is absorbed into your bloodstream.

Call your doctor at once if you have:

  • sudden weakness or ill feeling, fever, chills, sore throat, mouth sores, red or swollen gums, trouble swallowing;
  • easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;
  • pale or yellowed skin, dark colored urine, fever, confusion or weakness;
  • kidney problems --red or pink urine, little or no urinating, swelling, rapid weight gain;
  • liver problems --nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or
  • severe skin reaction --fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect silver sulfadiazine topical?

What other drugs will affect silver sulfadiazine topical?

Other drugs may interact with silver sulfadiazine topical, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Where can I get more information?

Where can I get more information?

Your doctor or pharmacist can provide more information about silver sulfadiazine topical.

This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.

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