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Home Knowledge Center Wellness Library taliglucerase alfa

taliglucerase alfa

Pronunciation: TAL i GLOO ser ase AL fa

Brand: Elelyso

What is the most important information I should know about taliglucerase alfa?

What is the most important information I should know about taliglucerase alfa?

Some people receiving a taliglucerase alfa injection have had a reaction when the medicine was injected, or up to 3 hours later. Tell your caregivers right away if you have a sudden headache, dizziness, warmth or tingling, chest pain, wheezing, nausea, or a red skin rash.

What is taliglucerase alfa?

What is taliglucerase alfa?

Taliglucerase is used as an enzyme replacement in people with Type I Gaucher disease in adults and children at least 4 years old.

Gaucher disease is a genetic condition in which the body lacks the enzyme needed to break down certain fatty materials (lipids). Lipids can build up in the body, causing symptoms such as easy bruising or bleeding, weakness, anemia, bone or joint pain, enlarged liver or spleen, or weakened bones that are easily fractured.

Taliglucerase may improve the condition of the liver, spleen, bones, and blood cells in people with Type I Gaucher disease. However, taliglucerase is not a cure for this condition.

Taliglucerase may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before receiving taliglucerase alfa?

What should I discuss with my healthcare provider before receiving taliglucerase alfa?

Tell your doctor if you are pregnant. It is not known whether this medicine will harm an unborn baby. However, having untreated or uncontrolled Type I Gaucher disease during pregnancy may cause new or worsening symptoms in the mother, or complications in the baby such as growth problems or bleeding. The benefit of treating your disease may outweigh any risks to the baby.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

How is taliglucerase alfa given?

How is taliglucerase alfa given?

Taliglucerase alfa is given as an infusion into a vein. A healthcare provider will give you this injection.

You may be given other medications to help prevent an allergic reaction. Keep using these medicines for as long as your doctor has prescribed.

You may be given other medications to prevent certain side effects of taliglucerase alfa.

Taliglucerase alfa is usually given every other week. Follow your doctor's dosing instructions very carefully.

Your doctor may occasionally change your dose to make sure you get the best results.

Taliglucerase alfa doses are based on weight (especially in children and teenagers). Your dose needs may change if you gain or lose weight.

What happens if I miss a dose?

What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your taliglucerase alfa injection.

What happens if I overdose?

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking taliglucerase alfa?

What should I avoid while taking taliglucerase alfa?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What are the possible side effects of taliglucerase alfa?

What are the possible side effects of taliglucerase alfa?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Some people receiving a taliglucerase alfa injection have had a reaction when the medicine was injected, or up to 3 hours later. Tell your caregivers right away if you have:

  • dizziness or feeling like you might pass out;
  • chest tightness, wheezing;
  • swelling in your face;
  • cough, throat irritation;
  • flushing (warmth, redness, or tingly feeling);
  • nausea, vomiting;
  • skin rash, itching, or redness.

Common side effects may include:

  • headache;
  • rash, itching, warmth or tingly feeling;
  • dizziness or tired feeling;
  • nausea, stomach pain, vomiting; or
  • joint pain, back pain, pain in your arms or legs.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect taliglucerase alfa?

What other drugs will affect taliglucerase alfa?

Other drugs may affect taliglucerase alfa, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Where can I get more information?

Where can I get more information?

Your doctor or pharmacist can provide more information about taliglucerase alfa.

This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.

Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.

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