How is tigecycline given?
Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.
Tigecycline is injected into a vein through an IV. You may be shown how to use an IV at home. Do not give yourself this medicine if you do not understand how to use the injection and properly dispose of needles, IV tubing, and other items used.
Tigecycline is usually given once every 12 hours. Follow your doctor's dosing instructions very carefully. The medicine must be given slowly, and each IV infusion can take 30 to 60 minutes to complete.
Tigecycline is a powder medicine that must be mixed with a liquid (diluent) in an IV bag before using it. If you are using the injections at home, be sure you understand how to properly mix and store the medication.
Prepare your dose only when you are ready to give an injection. After mixing, the liquid should appear as a yellow or orange color. Do not use if the medicine has changed to green or black, or if it has any particles in it. Call your pharmacist for a new prescription.
Do not give any of the following drugs through the same IV line used to give your tigecycline injection:
- amphotericin B;
- amphotericin B lipid complex;
- diazepam (Valium); or
Use a disposable needle and syringe only once. Follow any state or local laws about throwing away used needles and syringes. Use a puncture-proof "sharps" disposal container (ask your pharmacist where to get one and how to throw it away). Keep this container out of the reach of children and pets.
Use this medicine for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. Tigecycline will not treat a viral infection such as the common cold or flu.
Store unmixed powder at room temperature away from moisture and heat.
Mixed medicine in an IV bag may be kept at cool room temperature. But you must use the medicine within 24 hours (up to 6 hours in the vial and the other 18 hours in the IV bag).
Tigecycline mixed in an IV bag with 0.9% sodium chloride or 5% dextrose solution may be stored in a refrigerator and used within 48 hours.