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Home Knowledge Center Wellness Library tivozanib

tivozanib

Pronunciation: tye VOE zan ib

Brand: Fotivda

What is the most important information I should know about tivozanib?

What is the most important information I should know about tivozanib?

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

What is tivozanib?

What is tivozanib?

Tivozanib is used to treat advanced kidney cancer in adults, after at least two other cancer treatments did not work or have stopped working.

Tivozanib may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking tivozanib?

What should I discuss with my healthcare provider before taking tivozanib?

Tell your doctor if you have ever had:

  • heart problems;
  • high blood pressure;
  • a blood clot, heart attack, or stroke;
  • bleeding problems;
  • surgery, including oral surgery;
  • a wound that has not healed;
  • a thyroid disorder;
  • liver disease; or
  • an allergy to aspirin or yellow dye (tartrazine).

You may need to have a negative pregnancy test before starting this treatment.

Both men and women using this medicine should use effective birth control to prevent pregnancy. Tivozanib can harm an unborn baby if the mother or father is using this medicine.

Keep using birth control for at least 1 month after your last dose. Tell your doctor right away if a pregnancy occurs while either the mother or the father is using tivozanib.

Pregnancy may be less likely to occur while the mother or the father is using this medicine. Both men and women should still use birth control to prevent pregnancy because the medicine can harm an unborn baby.

Do not breastfeed while using this medicine, and for at least 1 month after your last dose.

How should I take tivozanib?

How should I take tivozanib?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Tivozanib is given in a 28-day treatment cycle. You may need to use the medicine only during the first 21 days of each cycle. Your doctor will determine how long to treat you with this medicine.

You may take tivozanib with or without food.

Swallow the capsule whole and do not crush, chew, break, or open it.

Your blood pressure will need to be checked often. You may also need blood or urine tests.

You may be given other medication to help prevent nausea, vomiting, or high blood pressure. Keep using these medicines for as long as your doctor has prescribed.

If you need surgery or dental work, tell your surgeon or dentist you currently use this medicine. You should stop taking tivozanib for at least 24 days before a planned surgery.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

What happens if I miss a dose?

Skip the missed dose and use your next dose at the regular time. Do not use two doses in the same day.

What happens if I overdose?

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose may cause severely high blood pressure.

What should I avoid while taking tivozanib?

What should I avoid while taking tivozanib?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What are the possible side effects of tivozanib?

What are the possible side effects of tivozanib?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • severe headache, confusion, dizziness;
  • a seizure;
  • chest pain, shortness of breath;
  • blurred vision, pounding in your neck or ears;
  • swelling in your lower legs, rapid weight gain;
  • any wound that will not heal;
  • easy bruising or bleeding (nosebleeds, bleeding gums);
  • signs of bleeding inside your body --weakness, dizziness; pink or brown urine; abnormal vaginal bleeding; bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;
  • signs of a blood clot --sudden numbness or weakness on one side of the body, chest pain, problems with vision or speech, pain or swelling in an arm or leg; or
  • kidney problems --swelling, puffy eyes, foamy urine.

Your cancer treatments may be delayed or permanently discontinued if you have certain side effects.

Common side effects may include:

  • nausea, vomiting, diarrhea, loss of appetite;
  • feeling weak or tired;
  • cough, hoarse voice;
  • mouth sores; or
  • abnormal blood tests.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect tivozanib?

What other drugs will affect tivozanib?

Other drugs may affect tivozanib, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Where can I get more information?

Where can I get more information?

Your pharmacist can provide more information about tivozanib.

This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.

Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.

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