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Home Knowledge Center Wellness Library treprostinil (inhalation)

treprostinil (inhalation)

Pronunciation: tre PROS ti nil

Brand: Tyvaso

What is the most important information I should know about treprostinil inhalation?

What is the most important information I should know about treprostinil inhalation?

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

 What is treprostinil inhalation?

What is treprostinil inhalation?

Treprostinil is used to treat pulmonary arterial hypertension (PAH). This medicine improves your ability to exercise and can help prevent your condition from getting worse.

Treprostinil may also be used for purposes not listed in this medication guide.

 What should I discuss with my healthcare provider before using treprostinil inhalation?

What should I discuss with my healthcare provider before using treprostinil inhalation?

You should not use treprostinil if you are allergic to it.

Tell your doctor if you have ever had:

  • bronchospasm (wheezing, chest tightness, trouble breathing);
  • low blood pressure;
  • bleeding problems; or
  • liver disease.

Tell your doctor if you are pregnant or breastfeeding.

 How should I use treprostinil inhalation?

How should I use treprostinil inhalation?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Do not swallow treprostinil inhalation. The medicine should be inhaled using only the Tyvaso inhalation system.

Treprostinil inhalation should be used only with a Tyvaso inhalation system. Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

Treprostinil inhalation is usually given 4 times per day at evenly spaced intervals during waking hours. Use exactly as directed on the label, or as prescribed by your doctor.

Do not mix other inhalation medicines with treprostinil in the Tyvaso inhalation system.

Wash your hands before preparing your treprostinil doses in the inhalation system.

Before your first dose of each day, twist off the top of one ampule and empty the contents into the medicine cup of the inhalation system. One ampule of treprostinil inhalation contains enough medicine for all 4 of a day's doses.

At the end of the day after your last dose, empty and rinse out the medicine cup, even if there is still some medicine left in it.

The effects of treprostinil inhalation will lessen over time between doses. Talk with your doctor if you need to time your dosing around any planned activities.

Do not use more than 12 breaths per treatment session, 4 times per day.

Use treprostinil regularly to get the most benefit. You should not reduce your dose or stop using treprostinil suddenly. Stopping suddenly may make your condition worse. Get your prescription refilled before you run out of medicine completely. Make sure you have a backup inhalation system available so as not to interrupt your treatment if one system stops working.

Call your doctor if your symptoms do not improve, or if they get worse while using treprostinil inhalation.

Store treprostinil ampules in their foil pouch at room temperature away from moisture, heat, and light. Once you have opened a foil pouch, the ampules in it should be used within 7 days.

Store the inhalation system upright and tightly capped with the plugs when not in use. Any treprostinil in the medicine cup must be used within 24 hours. Throw away any unused medicine at the end of the day after your last dose.

 What happens if I miss a dose?

What happens if I miss a dose?

Use the medicine as soon as you can. Do not use two doses at one time.

 What happens if I overdose?

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include headache, warmth or tingling, vomiting, diarrhea, or feeling light-headed.

 What should I avoid while using treprostinil inhalation?

What should I avoid while using treprostinil inhalation?

Avoid getting this medicine in your eyes. If contact does occur, rinse with water.

Avoid getting this medicine on your skin. If this medication gets on your skin, wash the area with soap and water.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.

 What are the possible side effects of treprostinil inhalation?

What are the possible side effects of treprostinil inhalation?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • a light-headed feeling, like you might pass out;
  • easy bruising or bleeding (nosebleeds, bleeding gums), or any bleeding that will not stop;
  • unexpected vaginal bleeding;
  • coughing up blood or vomit that looks like coffee grounds; or
  • blood in your urine or stools, black or tarry stools.

Common side effects may include:

  • cough, sore throat;
  • muscle, jaw or bone pain;
  • pain or irritation in your throat after use;
  • dizziness or feeling light-headed;
  • nausea, diarrhea;
  • headache; or
  • flushing (warmth, redness or tingling).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

 What other drugs will affect treprostinil inhalation?

What other drugs will affect treprostinil inhalation?

Other drugs may affect treprostinil, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

 Where can I get more information?

Where can I get more information?

Your doctor or pharmacist can provide more information about treprostinil inhalation.

This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.

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