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Home Knowledge Center Wellness Library velaglucerase alfa

velaglucerase alfa

Pronunciation: VEL a GLOO ser ase AL fa

Brand: VPRIV

What is the most important information I should know about velaglucerase alfa?

What is the most important information I should know about velaglucerase alfa?

An allergic reaction may occur during or shortly after infusion of this medicine. Tell your caregivers or get emergency medical help right away if you have any signs of a severe allergic reaction, such as headache, dizziness, fever, nausea, feeling weak or tired, and feeling like you might pass out.

What is velaglucerase alfa?

What is velaglucerase alfa?

Velaglucerase alfa contains an enzyme that occurs naturally in the body in healthy people. Some people lack this enzyme because of a genetic disorder. Velaglucerase alfa helps replace this missing enzyme in people with Type I Gaucher disease.

Gaucher disease is a genetic condition in which the body lacks the enzyme needed to break down certain fatty materials (lipids). Lipids can build up in the body, causing symptoms such as easy bruising or bleeding, weakness, anemia, bone or joint pain, enlarged liver or spleen, or weakened bones that are easily fractured.

Velaglucerase may improve the condition of the liver, spleen, bones, and blood cells in people with Type I Gaucher disease. However, velaglucerase is not a cure for this condition.

Velaglucerase may also be used for purposes not listed in this medication guide.

What should I discuss with my health care provider before receiving velaglucerase alfa?

What should I discuss with my health care provider before receiving velaglucerase alfa?

Tell your doctor if you are pregnant or breastfeeding.

It is not known whether velaglucerase alfa will harm an unborn baby. However, having untreated Type I Gaucher disease during pregnancy may cause complications such as miscarriage or stillbirth. Type I Gaucher disease also can get worse during pregnancy and may cause medical problems in both mother and baby. The benefit of treating this disease with velaglucerase alfa may outweigh any risks to the baby.

Velaglucerase alfa is not approved for use by anyone younger than 4 years old.

How is velaglucerase alfa given?

How is velaglucerase alfa given?

Velaglucerase alfa is given as an infusion into a vein. A healthcare provider will give you this injection.

Velaglucerase alfa is usually given every other week. Follow your doctor's dosing instructions.

Velaglucerase alfa must be given slowly, and the infusion can take at least 1 hour to complete.

Velaglucerase alfa doses are based on weight (especially in children and teenagers). Your dose needs may change if you gain or lose weight.

What happens if I miss a dose?

What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your velaglucerase alfa injection.

What happens if I overdose?

What happens if I overdose?

Since this medicine is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

What should I avoid while receiving velaglucerase alfa?

What should I avoid while receiving velaglucerase alfa?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What are the possible side effects of velaglucerase alfa?

What are the possible side effects of velaglucerase alfa?

Get emergency medical help if you have signs of an allergic reaction: hives; fever; chest discomfort, difficult breathing; swelling of your face, lips, tongue, or throat.

An allergic reaction may occur during or shortly after infusion of this medicine. Tell your caregivers or get emergency medical help right away if you have any signs of a severe allergic reaction, such as headache, dizziness, fever, nausea, feeling weak or tired, and feeling like you might pass out.

Common side effects may include:

  • headache;
  • dizziness;
  • feeling weak or tired;
  • nausea, stomach pain;
  • joint pain, back pain; or
  • fever.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect velaglucerase alfa?

What other drugs will affect velaglucerase alfa?

Other drugs may affect velaglucerase alfa, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Where can I get more information?

Where can I get more information?

Your doctor or pharmacist can provide more information about velaglucerase alfa.

This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.

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