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Home Knowledge Center Wellness Library zonisamide

zonisamide

Pronunciation: zoe NIS a mide

Brand: Zonegran

Zonisamide

slide 1 of 15, Zonisamide,

25 mg, capsule, blue/purple, imprinted with MYLAN 6725

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Zonisamide

slide 2 of 15, Zonisamide,

50 mg, capsule, purple/white, imprinted with MYLAN 6726

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Zonisamide

slide 3 of 15, Zonisamide,

100 mg, capsule, blue/purple, imprinted with MYLAN 6727

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Zonisamide

slide 4 of 15, Zonisamide,

100 mg, capsule, blue/purple, imprinted with MYLAN 6727

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Zonisamide

slide 5 of 15, Zonisamide,

25 mg, capsule, white, imprinted with APO, 25

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Zonisamide

slide 6 of 15, Zonisamide,

50 mg, capsule, gray/white, imprinted with APO, 50

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Zonisamide

slide 7 of 15, Zonisamide,

25 mg, capsule, white, imprinted with 258

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Zonisamide

slide 8 of 15, Zonisamide,

50 mg, capsule, gray/white, imprinted with 259

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Zonisamide

slide 9 of 15, Zonisamide,

25 mg, capsule, white, imprinted with W945

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Zonisamide

slide 10 of 15, Zonisamide,

50 mg, capsule, gray/white, imprinted with W946

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Zonisamide

slide 11 of 15, Zonisamide,

100 mg, capsule, orange/white, imprinted with W990

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Zonisamide

slide 12 of 15, Zonisamide,

100 mg, capsule, green/white, imprinted with G24, 100

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Zonisamide

slide 13 of 15, Zonisamide,

100 mg, capsule, brown/white, imprinted with 100 MG, IG 228

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Zonisamide

slide 14 of 15, Zonisamide,

100 mg, capsule, red/white, imprinted with APO, 100

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Zonisamide

slide 15 of 15, Zonisamide,

25 mg, white, imprinted with barr 25 mg, 827

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What is the most important information I should know about zonisamide?

What is the most important information I should know about zonisamide?

Taking zonisamide can cause permanent vision loss. Tell your doctor right away if you have any eye pain or redness or any changes in your vision.

Some people have thoughts about suicide while taking zonisamide. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor.

What is zonisamide?

What is zonisamide?

Zonisamide is used together with other medicines to treat partial seizures in adults and teenagers at least 16 years old.

Zonisamide may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking zonisamide?

What should I discuss with my healthcare provider before taking zonisamide?

You should not use zonisamide if you are allergic to it.

You may not be able to take zonisamide if you have ever had a severe allergic to a sulfa drug.

Tell your doctor if you have ever had:

  • liver disease;
  • kidney disease;
  • high levels of ammonia;
  • stomach flu or illness causing diarrhea;
  • a growth disorder;
  • a bone disorder that causes soft or weak bones or low bone mineral density;
  • depression, or suicidal thoughts or actions;
  • if you have ever had metabolic acidosis (too much acid in your blood); or
  • if you have been on a ketogenic diet (high-fat, high-protein, low-carb).

Some people have thoughts about suicide while taking zonisamide. Your doctor will need to check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.

Zonisamide may harm an unborn baby. Use effective birth control to prevent pregnancy, and tell your doctor if you become pregnant.

If you are pregnant, your name may be listed on a pregnancy registry to track the effects of zonisamide on the baby.

You should not breastfeed while using zonisamide.

Zonisamide is not approved for use by anyone younger than 16 years old.

How should I take zonisamide?

How should I take zonisamide?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Zonisamide can be taken with or without food.

Swallow the capsule whole and do not crush, chew, break, or open it.

While using zonisamide, you may need frequent blood tests.

Do not stop using zonisamide suddenly, even if you feel fine. Stopping suddenly may cause increased seizures. Follow your doctor's instructions about tapering your dose.

Do not share this medicine with another person, even if they have the same symptoms you have.

Store at room temperature away from moisture, heat, and light.

What happens if I miss a dose?

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include slow heart rate, feeling light-headed, fainting, and slow or shallow breathing.

What should I avoid while taking zonisamide?

What should I avoid while taking zonisamide?

Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.

Drinking alcohol with this medicine can cause side effects.

What are the possible side effects of zonisamide?

What are the possible side effects of zonisamide?

Get emergency medical help if you have signs of an allergic reaction: any form of skin rash, hives; fever, swollen glands, feeling weak or tired, severe muscle pain, unusual bruising or bleeding; yellowing of your skin or eyes; difficult breathing; swelling of your face, lips, tongue, or throat.

Report any new or worsening symptoms to your doctor, such as: sudden mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), depressed, or have thoughts about suicide or hurting yourself.

Call your doctor at once if you have:

  • eye pain or redness or any changes in your vision;
  • decreased sweating, feeling very hot;
  • signs of metabolic acidosis --confusion, vomiting, lack of energy, irregular heartbeats;
  • symptoms of a blood cell disorder --fever, chills, body aches, flu symptoms, sores in your mouth and throat;
  • symptoms of a kidney stone --severe pain in your stomach or lower back, blood in your urine;
  • increased or worsening seizures;
  • the first sign of any skin rash, no matter how mild; or
  • severe skin reaction --fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

Common side effects may include:

  • drowsiness, dizziness;
  • problems with memory or concentration;
  • feeling agitated or irritable;
  • loss of coordination, trouble walking; or
  • loss of appetite.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect zonisamide?

What other drugs will affect zonisamide?

Taking this medicine with other drugs that make you sleepy can worsen this effect. Ask your doctor before taking zonisamide with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety or depression.

Other drugs may interact with zonisamide, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Where can I get more information?

Where can I get more information?

Your pharmacist can provide more information about zonisamide.

This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.

Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.

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