Skip to main navigation Skip to main content Skip to footer
  • For Individuals & Families
  • For Medicare
  • For Providers
  • For Brokers
  • Search
    Search
    Español
  • For Employers:
  • For Employers:
  • Plans and Services

    Plans and Services

  • Who We Serve

    Who We Serve

  • Employer Resources

    Employer Resources

  • Log in to Employer Portal
  • Log in to Employer Portal
  • Plans and Services

    Plans and Services

  • Who We Serve

    Who We Serve

  • Why Cigna Healthcare
  • Employer Resources

    Employer Resources

  • Home Employers Cost Control Strategies Embarc Benefit Protection

    Embarc Benefit Protection

    Protecting customers from the high costs of breakthrough gene therapy drugs.

    Building a new benefits package?

    Making Gene Therapy Drugs More Accessible

    The Embarc Benefit Protection® solution brings together the health services, medical management, and specialty pharmacy expertise of Cigna HealthcareSM*, eviCoreTM, Accredo®, and Express Scripts®. This solution helps shield health plans and customers from the cost of breakthrough gene therapy drugs and helps to ensure access for those who need them.

    Our Embarc Benefit Protection solution includes:

    LUXTURNA®(voretigene neparvovec-rzyl)

    This is the first FDA-approved prescription gene therapy for people with inherited retinal disease at a cost of $850K (both eyes).1

    ZOLGENSMA®(onasemnogene abeparvovec-xioi)2

    A $2.1M gene therapy for children under 2 years old with spinal muscular atrophy a potentially life-threatening condition.3

    The financial protection against the high cost of ZOLGENSMA applies only to children born after the Embarc Benefit Protection solution is effective for their group health plan.

    ZYNTEGLO®(betibeglogene autotemcel)4

    Used for a blood disorder known as beta thalassemia in patients who cannot make enough beta-globin and require regular red blood cell transfusions at a cost of $2.8M.5

    For existing Embarc Benefit Protection clients with effective dates of 08/01/2022 or earlier, all members who meet the solution’s clinical and network criteria for ZYNTEGLO will be able to access the drug through Embarc Benefit Protection. For clients who join Embarc Benefit Protection after 08/01/2022, Embarc Benefit Protection for ZYNTEGLO is only applicable to members who first became eligible for coverage under the Plan on and after 08/19/2022.

    SKYSONA®(elivaldogene autotemcel)

    With a cost of $3M,5 this gene therapy is for patients 4-17 years of age with early, active cerebral adrenoleukodystrophy (CALD)—a rare neuro-degenerative disease that can lead to progressive, irreversible loss of neurologic function and death.

    HEMGENIX®(etranacogenedezaparvovec-drlb)6

    A one-time gene therapy drug with a projected cost of $3.5M7 for adults living with hemophilia B who currently use factor IX prophylaxis therapy, or have current or historical life-threatening hemorrhage, or have repeated, serious spontaneous bleeding episodes.

    For existing Embarc Benefit Protection clients with effective dates of March 1, 2023 or earlier, all customers who meet the solution’s clinical and network criteria for HEMGENIX will be able to access the drug through Embarc Benefit Protection. For clients that join Embarc Benefit Protection after March 1, 2023, the financial protection extends only to customers who join the underlying medical coverage 30 days or more after the client is effective in Embarc Benefit Protection (i.e., late enrollees).

    ROCTAVIANTM (valoctocogene roxaparvovec-rvox)8

    A one-time gene therapy drug with a projected cost of $2.9M9 indicated for the treatment of adults with severe hemophilia A.

    CASGEVYTM (exagamglogene autotemcel)10

    A one-time gene therapy drug with a projected cost of $2.2M11 indicated for the treatment of adults with sickle cell disease.

    LYFGENIATM (lovotibeglogene autotemcel)12

    A one-time gene therapy drug with a projected cost of $3.1M13 indicated for the treatment of adults with sickle cell disease.

    Did you know?

    By 2032, annual gene therapy sales globally are expected to reach $38.76 billion.14 If health plans cannot afford to cover these drugs, the patients that need them will not have access.

    *Offered by Cigna Health and Life Insurance Company

    View Cigna Healthcare Company Names

    1 Drugs.com 2024: price of LUXTURNA

    2 The financial protection against the high cost of ZOLGENSMA applies only to children born after the Embarc Benefit Protection solution is effective for their group health plan.

    3 Drugs.com 2023: price of ZOLGENSMA

    4 For existing Embarc Benefit Protection clients with effective dates of 08/01/2022 or earlier, all members who meet the solution’s clinical and network criteria for ZYNTEGLO will be able to access the therapy through Embarc Benefit Protection. For clients who join Embarc Benefit Protection after 08/01/2022, the financial protection extends only to customers who enroll in the underlying medical coverage 30 days or more after the client is effective in Embarc Benefit Protection.

    5 bluebird bio 2022: published price of ZYNTEGLO and SKYSONA from the manufacturer

    6 For existing Embarc Benefit Protection clients with effective dates of 03/01/2023 or earlier, all customers who meet the solution’s clinical and network criteria for HEMGENIX will be able to access the therapy through Embarc Benefit Protection. For clients who join Embarc Benefit Protection after 03/01/2023, the financial protection extends only to customers who join the underlying medical coverage 30 days or more after the client is effective in Embarc Benefit Protection.

    7 CSL Behring 2023: published price of HEMGENIX from the manufacturer

    8 For existing Embarc Benefit Protection clients with effective dates of 09/01/2023 or earlier, all customers who meet the solution’s clinical and network criteria for ROCTAVIAN will be able to access the therapy through Embarc Benefit Protection. For clients who join Embarc Benefit Protection after 09/01/2023, the financial protection extends only to customers who join the underlying medical coverage 30 days or more after the client is effective in Embarc Benefit Protection.

    9 BioMarin 2023: published price of ROCTAVIAN

    10 For existing Embarc Benefit Protection clients with effective dates of 04/01/2024 or earlier, all customers who meet the solution’s clinical and network criteria for CASGEVY will be able to access the therapy through Embarc Benefit Protection. For clients who join Embarc Benefit Protection after 04/01/2024, the financial protection extends only to customers who join the underlying medical coverage 30 days or more after the client is effective in Embarc Benefit Protection.

    11 Vertex Pharmaceuticals Inc. 2023: published price of CASGEVY

    12 For existing Embarc Benefit Protection clients with effective dates of 04/01/2024 or earlier, all customers who meet the solution’s clinical and network criteria for LYFGENIA will be able to access the therapy through Embarc Benefit Protection. For clients who join Embarc Benefit Protection after 04/01/2024, the financial protection extends only to customers who join the underlying medical coverage 30 days or more after the client is effective in Embarc Benefit Protection.

    13 bluebird bio 2023: published price of LYFGENIA

    14 Precedence Research, Gene Therapy Market Size, Growth, Trends, Report 2023-2032, precedenceresearch.com, accessed January 29, 2024

    LUXTURNA is the registered trademark of Spark Therapeutics, Inc. and ZOLGENSMA is the registered trademark of AveXis, Inc. ZYNTEGLO and SKYSONA are both registered trademarks of bluebird bio, Inc. HEMGENIX is the registered trademark of CSL Behring, L.L.C. ROCTAVIAN is a registered trademark of BioMarin. CASGEVY is a registered trademark of Vertex Pharmaceuticals Inc. LYFGENIA is a registered trademark of bluebird bio, Inc.

    Product availability may vary by location and plan type and is subject to change. For costs and details contact a Cigna Healthcare representative.

    All Cigna Healthcare products and services are provided exclusively by or through operating subsidiaries of The Cigna Group, including Cigna Health and Life Insurance Company (Bloomfield, CT.) (CHLIC), eviCore healthcare MSI, LLC (d/b/a/ eviCore healthcare), Express Scripts, Inc., Accredo Health Group, Inc., or their affiliates.

    In Utah, all products and services are provided by Cigna Health and Life Insurance Company (Bloomfield, CT). Policy forms: OK – HP-APP-1 et al., OR – HP-POL38 02-13, TN – HP-POL43/HC-CER1V1 et al. (CHLIC); GSA-COVER, et al. (CHC-TN).

    © 2024 Cigna Healthcare.

    Some content provided under license

    Let's Get Started

    Thank you for your interest in Cigna Healthcare. Please provide some basic information about your company and a representative will contact you.

    First Name Last Name Email Address Company City State Choose a State Alabama Alaska Arizona Arkansas California Colorado Connecticut Delaware District Of Columbia Florida Georgia Hawaii Idaho Illinois Indiana Iowa Kansas Kentucky Louisiana Maine Maryland Massachusetts Michigan Minnesota Mississippi Missouri Montana Nebraska Nevada New Hampshire New Jersey New Mexico New York North Carolina North Dakota Ohio Oklahoma Oregon Pennsylvania Rhode Island South Carolina South Dakota Tennessee Texas Utah Vermont Virginia Washington West Virginia Wisconsin Wyoming ------ Alberta British Columbia Manitoba New Brunswick Newfoundland and Labrador Nova Scotia Ontario Prince Edward Island Saskatchewan Quebec ------ American Samoa Guam Federated States Of Micronesia Marshall Islands Northern Mariana Islands Military Americas Military Europe/ME/Canada Military Pacific Northwest Territories Nunavut Palau Puerto Rico Virgin Islands Yukon Territory Zip Code 12345 or 12345-2345 Country Choose a Country United States Canada United Kingdom ------------ Andorra United Arab Emirates Afghanistan Antigua and Barbuda Anguilla Albania Armenia Angola Antarctica Argentina American Samoa Austria Australia Aruba Aland Islands Azerbaijan Bosnia and Herzegovina Barbados Bangladesh Belgium Burkina Faso Bulgaria Bahrain Burundi Benin Saint Barthelemy Bermuda Brunei Bolivia Bonaire, Saint Eustatius and Saba Brazil Bahamas Bhutan Bouvet Island Botswana Belarus Belize Cocos Islands Democratic Republic of the Congo Central African Republic Republic of the Congo Switzerland Ivory Coast Cook Islands Chile Cameroon China Colombia Costa Rica Cuba Cape Verde Curacao Christmas Island Cyprus Czech Republic Germany Djibouti Denmark Dominica Dominican Republic Algeria Ecuador Estonia Egypt Western Sahara Eritrea Spain Ethiopia Finland Fiji Falkland Islands Micronesia Faroe Islands France Gabon Grenada Georgia French Guiana Guernsey Ghana Gibraltar Greenland Gambia Guinea Guadeloupe Equatorial Guinea Greece South Georgia and the South Sandwich Islands Guatemala Guam Guinea-Bissau Guyana Hong Kong Heard Island and McDonald Islands Honduras Croatia Haiti Hungary Indonesia Ireland Israel Isle of Man India British Indian Ocean Territory Iraq Iran Iceland Italy Jersey Jamaica Jordan Japan Kenya Kyrgyzstan Cambodia Kiribati Comoros Saint Kitts and Nevis North Korea South Korea Kuwait Cayman Islands Kazakhstan Laos Lebanon Saint Lucia Liechtenstein Sri Lanka Liberia Lesotho Lithuania Luxembourg Latvia Libya Morocco Monaco Moldova Montenegro Saint Martin Madagascar Marshall Islands Macedonia Mali Myanmar Mongolia Macao Northern Mariana Islands Martinique Mauritania Montserrat Malta Mauritius Maldives Malawi Mexico Malaysia Mozambique Namibia New Caledonia Niger Norfolk Island Nigeria Nicaragua Netherlands Norway Nepal Nauru Niue New Zealand Oman Panama Peru French Polynesia Papua New Guinea Philippines Pakistan Poland Saint Pierre and Miquelon Pitcairn Puerto Rico Palestinian Territory Portugal Palau Paraguay Qatar Reunion Romania Serbia Russia Rwanda Saudi Arabia Solomon Islands Seychelles Sudan Sweden Singapore Saint Helena Slovenia Svalbard and Jan Mayen Slovakia Sierra Leone San Marino Senegal Somalia Suriname South Sudan Sao Tome and Principe El Salvador Sint Maarten Syria Swaziland Turks and Caicos Islands Chad French Southern Territories Togo Thailand Tajikistan Tokelau East Timor Turkmenistan Tunisia Tonga Turkey Trinidad and Tobago Tuvalu Taiwan Tanzania Ukraine Uganda United States Minor Outlying Islands Uruguay Uzbekistan Vatican Saint Vincent and the Grenadines Venezuela British Virgin Islands U.S. Virgin Islands Vietnam Vanuatu Wallis and Futuna Samoa Kosovo Yemen Mayotte South Africa Zambia Zimbabwe I am a(n): Select... Seeking coverage for myself and/or my family Seeking coverage for my small business 25 employees Employer looking to offer coverage through Cigna Employer with international presence looking for information about Cigna benefits Employee of a company who currently has Cigna benefits Employer currently offering Cigna Broker who is looking to quote Cigna Other (please explain) If you chose "Other" above, please explain: Employee Size Select... 1-2 3-10 11-24 25-50 51-99 100-249 250-499 500-4,999 5,000+ 5,000+ multiple states Business Phone +1 123 456 5678

    I consent to receive calls or texts from Cigna and its affiliates that may deliver an autodialed or prerecorded telemarketing message at the phone number provided above. I understand that my consent is not required to purchase products or services.

    Comments Contact Me

    You may be contacted by a licensed insurance agent.

    Thank you
    Your data has been submitted.
    Oops!
    There was a problem submitting your data, please try again later.
    I want to...
  • Get an ID card
  • File a claim
  • View my claims and EOBs
  • Check coverage under my plan
  • See prescription drug list
  • Find an in-network doctor, dentist, or facility
  • Find a form
  • Find 1095-B tax form information
  • View the Cigna Healthcare Glossary
  • Contact Cigna Healthcare
  • Audiences
  • Individuals and Families
  • Medicare
  • Employers
  • Brokers
  • Providers
  • Secure Member Sites
  • myCigna member portal
  • Health Care Provider portal
  • Cigna for Employers
  • Client Resource Portal
  • Cigna for Brokers
  • The Cigna Group Information
  • About Cigna Healthcare
  • The Cigna Group
  • Careers
  • Newsroom
  • Investors
  • Suppliers
  • Third Party Administrators
  • International
  • Evernorth Health Services
  • Cigna Healthcare. All rights reserved.
  • Privacy
  • Terms of Use
  • Legal
  • Product Disclosures
  • Company Names
  • Customer Rights
  • Accessibility
  • Report Fraud
  • Sitemap
  • Washington Consumer Health Data Privacy Notice
  • Cookie Settings
  • Disclaimer

    Individual and family medical and dental insurance plans are insured by Cigna Health and Life Insurance Company (CHLIC), Cigna HealthCare of Arizona, Inc., Cigna HealthCare of Illinois, Inc., Cigna HealthCare of Georgia, Inc., Cigna HealthCare of North Carolina, Inc., Cigna HealthCare of South Carolina, Inc., and Cigna HealthCare of Texas, Inc. Group health insurance and health benefit plans are insured or administered by CHLIC, Connecticut General Life Insurance Company (CGLIC), or their affiliates (see a listing of the legal entities that insure or administer group HMO, dental HMO, and other products or services in your state). Accidental Injury, Critical Illness, and Hospital Care plans or insurance policies are distributed exclusively by or through operating subsidiaries of The Cigna Group Corporation, are administered by Cigna Health and Life Insurance Company, and are insured by either (i) Cigna Health and Life Insurance Company (Bloomfield, CT). The Cigna Healthcare name, logo, and other Cigna Healthcare marks are owned by The Cigna Group Intellectual Property, Inc.

    All insurance policies and group benefit plans contain exclusions and limitations. For availability, costs and complete details of coverage, contact a licensed agent or Cigna Healthcare sales representative. This website is not intended for residents of Arizona and New Mexico.

    Selecting these links will take you away from Cigna.com to another website, which may be a non-Cigna Healthcare website. Cigna Healthcare may not control the content or links of non-Cigna Healthcare websites. Details